[Environmental radiation dose monitor after 125I radioactive seed implantation].

Ai Zheng

State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China.

Published: June 2007

Background & Objective: Medical imaging-guided 125I radioactive seed implantation is a new method of mini-invasive therapy. As a component of combined therapy for malignant tumors, 125I implantation has benefits of minimal invasion, accurate position fixing, and certain clinical effects, and has been widely applied to treat tumors at present. Also the environmental phototoxis and radiation protection have been highly regarded. This study was to investigate the environmental radiation dose monitor after 125I radioactive seed implantation.

Methods: From Oct. 2004 to Dec. 2005, 20 patients with malignant tumors were randomly selected in this study after 125I radioactive seed implantation. Environmental radiation dose was detected right after operation and 2, 4 and 6 months later with gamma-ray equipment.

Results: With the increase of the distance from radioactive source, the radiation dose decreased quickly. The detected dose was close to a natural background radiation dose at a distance of 50 cm from radioactive source. With time passing, the environmental radiation dose was attenuated and the detected dose was close to natural background after 6 months.

Conclusions: Addition to the isolation and shielding protection before and after 125I radioactive seed implantation, distance protection and time protection should be considered. With necessary strict protection, 125I implantation is safe to patients and environment.

Download full-text PDF

Source

Publication Analysis

Top Keywords

radiation dose
24
125i radioactive
20
radioactive seed
20
seed implantation
12
environmental radiation
12
dose
8
dose monitor
8
monitor 125i
8
malignant tumors
8
125i implantation
8

Similar Publications

A combination of gold nanoparticles and laser photobiomodulation to boost antioxidant defenses in the recovery of muscle injuries caused by Bothrops jararaca venom.

Lasers Med Sci

January 2025

Laboratory of Pathophysiology Experimental, Postgraduate Program in Health Sciences, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.

Unlabelled: This study aimed to evaluate gold nanoparticles (GNPs) and photobiomodulation (PBM), associated with antibothropic serum (AS), to treat a muscle lesion induced by Bothrops jararaca venom.

Methods: 108 Swiss male mice were used, divided into nine groups (n = 12) with different combinations of treatments. Animals were inoculated with 250 µg of B.

View Article and Find Full Text PDF

Three-Dimensional CT for Preprocedural Planning of PCI for Ostial Right Coronary Artery Lesions: A Randomized Controlled Pilot Trial.

Circ Cardiovasc Interv

January 2025

Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium (D.M.F.v.d.B., E.M.P., E.W., D.C., E.M., B.F., M.V., J.D., K.A.).

Background: Geographic stent-ostium mismatch is an important predictor of target lesion failure after percutaneous coronary intervention of an aorto-ostial right coronary artery lesion. Optimal visualization of the aorto-ostial plane is crucial for precise stent implantation at the level of the ostium. This study investigates whether preprocedural 3-dimensional computed tomography (3DCT), with determination of the optimal viewing angle, would allow for more precise stent implantation and reduce procedure time, contrast, and radiation dose.

View Article and Find Full Text PDF

Dosimetric Planning Comparison for Left Ventricle Avoidance in Non-small Cell Lung Cancer Radiotherapy.

Cureus

December 2024

Physics and Engineering, London Regional Cancer Program, London, CAN.

Introduction: Radiation may unintentionally injure myocardial tissue, potentially leading to radiation-induced cardiac disease (RICD), with the net benefit of non-small cell lung cancer (NSCLC) radiotherapy (RT) due to the proximity of the lung and heart. RTOG-0617 showed a greater reduction in overall survival (OS) comparing higher doses to standard radiation doses in NSCLC RT. VHeart has been reported as an OS predictor in the first- and fifth-year follow-ups.

View Article and Find Full Text PDF

Background: Different doses of radiotherapy (RT) exert diverse effects on tumor immunity, although the precise irradiation method remains unknown. This study sought to elucidate the influence of combining different doses of RT with immune checkpoint inhibitors (ICIs) on the infiltration of CD8T cells within tumors, thereby augmenting the anti-tumor response.

Methods: Constructing a mouse model featuring bilateral lung cancer tumors subjected to high and low dose irradiation, the analysis of RNA transcriptome sequencing data and immunohistochemical validation for tumors exposed to various dosages guided the selection of the optimal low-dose irradiation scheme.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!