The influence of polyunsaturated fatty acids of mare 's milk fat on the cellular composition of the peripheral blood was investigated in male rats after a prolonged period of feeding. Animals were fed with isocaloric purified diet, part fats which on 30% (on caloricity) of fat marers milk (in experements group), in control groups - combination of lard and sunflower oil in which the ratio of fatty acids omega-6/omega-3 was equal to 0,76. At the end of the 6-th week of feeding (on the 6-th day after a single immunization with a 5% sheep erythrocyte suspension) the immunized animals have demonstrated leucocytosis that was marked by a considerable rise in the level of neutrophils and lymphocytes and a twofold increase of monocyte number. Such characteristic changes in leucocytogram exept low monocytosis were not revealed in immunized rats at the end of the 8-th week of feeding (on the 13-th day after a repeated immunization).
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