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Long-term hemodynamic responses and reverse remodeling after pharmacotherapy in HFpEF versus HFrEF: a systematic review and meta-analysis.
Am J Physiol Heart Circ Physiol
January 2025
Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Department of Cardiology, Amsterdam, The Netherlands.
The acute response to therapeutic afterload reduction differs between heart failure with preserved (HFpEF) versus reduced ejection fraction (HFrEF), with larger left ventricular (LV) stroke work augmentation in HFrEF compared to HFpEF. This may (partially) explain the neutral effect of HFrEF-medication in HFpEF. It is unclear whether such differences in hemodynamic response persist and/or differentially trigger reverse remodeling in case of long-term afterload reduction.
View Article and Find Full Text PDFA PFO Mediated Persistent Right-to-Left Shunt, a Worse Form of Platypnea-Orthodeoxia Syndrome.
Heart Lung Circ
January 2025
Section of Cardiology, University of Manitoba, Max Rady College of Medicine, Winnipeg, MB, Canada. Electronic address: https://www.twitter.com/KassMalek.
Association of Impaired Relaxation Mitral Inflow Pattern (Grade 1 Diastolic Function) with Long-term Non-Cardiovascular and Cardiovascular Mortality.
J Am Soc Echocardiogr
January 2025
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Background: Abnormalities of left ventricular (LV) diastolic function are established independent predictors of heart failure (HF) and mortality.
Objectives: To determine whether the association of diastolic function with all-cause mortality is driven by cardiovascular or non-cardiovascular death and if impaired relaxation mitral inflow filling pattern is a risk marker.
Methods: Diastolic function was graded by the Mayo Clinic algorithm utilizing the well characterized prospective Olmsted County Heart Function Study.
The relationship between different ventricular rate control levels and cardiac remodeling in early persistent atrial fibrillation: a prospective cohort study.
Front Cardiovasc Med
January 2025
Department of Cardiovascular Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia, with ventricular rate control being a critical therapeutic target. However, the optimal range for ventricular rate control remains unclear. Additionally, the relationship between different levels of ventricular rate control and cardiac remodeling in patients with atrial fibrillation remains unclear.
View Article and Find Full Text PDFIncarcerated Left Paraduodenal Hernia as a Rare Cause of Acute Abdomen: A Case Report and Literature Review.
Cureus
December 2024
General Surgery, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, IND.
Internal hernias are one of the rare causes of intestinal obstruction and usually is the diagnosis of exclusion. Para-duodenal hernias (PDH) are rare congenital disorders that occur due to malrotation of the midgut in the embryonic phase of development. They can be asymptomatic or can present as an incarcerated, strangulated, or even obstructed internal hernia.
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