Novel ebselen-porphyrin conjugates: synthesis and nucleic acid interaction study.

Bioorg Med Chem Lett

Department of Chemistry, Wuhan University, Wuhan 430072, PR China.

Published: August 2007

Novel porphyrins bearing ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]-one) moiety were synthesized and characterized. Their interactions with herring sperm DNA were studied by means of UV-visible, fluorescence, circular dichroism spectroscopy, and gel electrophoresis.

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http://dx.doi.org/10.1016/j.bmcl.2007.05.074DOI Listing

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