Objectives: To find the evolution of the consumption of alcohol, tobacco and other drugs among adolescents in an urban area.
Design: Descriptive, cross-sectional study using a self-administered questionnaire.
Setting: Secondary school (middle-class urban area).
Participants And Measurements: Six hundred and seventy-eight students took part in the years 1997, 2001, and 2004.
Measurements And Main Results: The questionnaire included questions on age, sex and consumption of toxic substances. The following figures are given in order of the year of study. We studied 172, 249, and 257 adolescents, with a mean age of 14 (interval, 12-17) and equality of sexes. The proportion of adolescents with no consumption of toxic substances increased (21%+/-3.1%; 34%+/-3.0% 56%+/-3.1%; P<.001, chi2), basically because alcohol consumption dropped (58%+/-3.6%; 61%+/-3.2%; 41%+/-3.1%; P<.001, chi2), although its weekend consumption increased (84%+/-2.6%; 85%+/-2.2%; 96%+/-1.2%; P<.05, chi2), especially of spirits. Tobacco consumption increased (12%+/-2.4%; 21%+/-2.3%; 29%+/-2.4%; P<.001, chi2) with a pattern of daily smoking (9%+/-0.6%; 34%+/-3.2%; 47%+/-3.1%; P<.01, chi2). The consumption of illegal rugs also increased (9%+/-0.6%; 24%+/-2.8%; 16%+/-2.4%; P<.001, chi2), with an intermittent pattern of consumption (87%+/-1.6%; 71%+/-2.3%; 85%+/-1.8). Cannabis is the most used drug (>90%), cocaine use fell and design drug use increased. Age affected consumption, but sex did not.
Conclusions: In the last 8 years the consumption of toxic substances among adolescents has dropped, mainly because of less alcohol consumption. However, new forms of consumption of alcohol and other illegal drugs, especially at weekends, emerged and daily consumption of tobacco increased.
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http://dx.doi.org/10.1157/13106285 | DOI Listing |
Transplant Cell Ther
January 2025
Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati, Cincinnati, OH.
Background: HSCT conditioning regimens cause massive lysis of hematopoietic cells with release of toxic intracellular molecules into the circulation.
Objectives: To describe the response to oxidative stress early after hemopoietic stem cell transplantation (HSCT) and assess the association of early oxidative stress with later transplant outcomes.
Study Design: Key components of in the body's physiological response to oxidative stress were studied in a cohort of 122 consecutive pediatric allogeneic HSCT recipients.
Cancer
January 2025
Fox Chase Cancer Center, Temple University Health System, Philadelphia, Pennsylvania, USA.
Background: Little is known about the role that charitable copay assistance (CPA) plays in addressing access to care and financial distress. The study sought to evaluate financial distress and experience with CPA among patients with cancer and autoimmune disease.
Methods: This is a national cross-sectional self-administered anonymous electronic survey conducted among recipients of CPA to cover the costs of a drug for cancer or autoimmune disease.
Microbiol Spectr
January 2025
Department of Biology and Chemistry, Changwon National University, Changwon, South Korea.
Unlabelled: Global aquaculture production faces the challenge of biologically cycling nitrogenous waste. Biofloc technology (BFT) systems offer the potential to reduce water consumption and eliminate waste products by using beneficial microorganisms to convert waste into usable nutrients or non-toxic molecules. Unlike flow-through systems (FTS), which depend on continuous water exchange and result in higher operational costs as well as limited microbiome stability, BFT operates without the need for constant water exchange.
View Article and Find Full Text PDFCancer Med
January 2025
Centre for Public Health, Queen's University Belfast, Belfast, UK.
Background: This study investigated and compared the impact of financial toxicity (FT) on the health-related quality of life (HRQoL) and financial well-being of cancer patients and survivors in the United Kingdom (UK) and United States (US).
Methods: UK & US participants (n = 600) completed an online questionnaire that consisted of a validated FT instrument (COmprehensive Score for financial Toxicity-COST), a standardised HRQoL instrument (EQ-5D-5L) and questions related to their financial well-being. Tobit regression models and descriptive statistics plus χ tests were used to analyse the association between FT and (i) HRQoL whilst controlling for sociodemographic characteristics; and (ii) financial well-being.
Curr Pharm Des
January 2025
Shandong Provincial Key Medical and Health Laboratory of Hydrogen Biomedical Research & Key Laboratory of Major Diseases and Hydrogen Medical Translational Applications in Universities of Shandong Province, Taishan Institute for Hydrogen Biomedical Research, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.
Molecular hydrogen (H2) is considered a biological antioxidant. Hydrogen-rich Water (HRW) is regular water that contains dissolved H2 and has become more widely used in recent years. This review summarizes the basic research and clinical applications of HRW consumption to support its use for daily health and clinical treatment.
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