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To find unknown celestial bodies is one of main goals in mankind's universe exploration, and outlier mining is a kind of effective way of finding unknown celestial bodies from mass spectrum data. In the present work, using VC++ and Oracle9i as development tools, an outlier mining system for star spectra is designed and realized, and its software architecture and function modules are outlined. At the same time, the system's key components such as star spectrum data preprocessing based on median filters, clustering of star spectrum data based on distance, outlier mining of star spectrum data based on distance support and three-dimensional visualization of star spectrum outlier based on PCA, are elaborated. The preliminary experimental results based on SDSS star spectrum data show that the system is workable for outlier mining of celestial body spectrum data, and a new kind of effective way of finding unknown and peculiar celestial body spectrum data.
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BMC Infect Dis
March 2025
Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Background: Mycoplasma pneumoniae (MP) is a common bacterial respiratory infection that can cause pneumonia, particularly in children. Previously published data have highlighted the high incidence of viral co-infections and the problem of increasing macrolide resistance in MP worldwide.
Aims: (1) to estimate the impact of viral infections circulating in a local population on the spectrum of co-infection in hospitalized children with Mycoplasma pneumoniae pneumonia (MPP), (2) to determine if there are differences in resistance mutation rate for samples from hospitals of Russia located in the European and Far East, (3) to describe genomic characteristics of MP from Russian patients during the MPP outbreaks in the fall-winter of 2023-2024.
Sci Rep
March 2025
Department of Neurology, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.
Biallelic pathogenic variants at TK2 lead to a severe and progressive myopathy (TK2d). For a disease with unspecific clinical findings, and the possibility of a supplementation therapy that changes the natural history of the disease, highlighting clinical features that increase suspicion and accelerate diagnosis is essential. Clinical and genetic findings of 36 Brazilian patients with TK2d were identified and presented in this work.
View Article and Find Full Text PDFEncephale
March 2025
Centre Ressource de Réhabilitation Psychosociale et de Remédiation Cognitive (CRR), Hôpital Le Vinatier, Centre National de la Recherche Scientifique (CNRS) et Université de Lyon, Bron, France.
Objective: Neuropsychological tests measuring executive functions are useful for identifying specific cognitive disorders, but they have limits for characterizing executive dysfunction in everyday activities. This study aims to investigate the socio-demographic, clinical, and psychosocial features associated with executive functions in patients with schizophrenia, bipolar, and autism spectrum disorders using a Paper Multiple Errands Test.
Patients Or Materials And Methods: A total of 1071 adults with schizophrenia spectrum disorder, 329 with bipolar spectrum disorder, and 254 with autism spectrum disorder were recruited from the French National Centers of Reference for Psychiatric Rehabilitation (REHABase) cohort between January 2016 and October 2022.
Ann Clin Lab Sci
January 2025
Department of Laboratory Medicine, Wenzhou People's Hospital, The Third Affiliated Hospital of Shanghai University, The Wenzhou Third Clinical College of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
Objective: This study aimed to ascertain serum bile acid levels and explore the diagnostic value of differential bile acids in patients with intrahepatic cholestasis of pregnancy (ICP).
Methods: 94 cases of ICP patients admitted to Wenzhou People's Hospital from Oct 2020 to July 2023 were selected as the ICP group, and 184 women who underwent normal prenatal examination in the same period as the healthy control group. The baseline data and 15 kinds of serum bile acid spectrum characteristics of the two groups of pregnant women were compared, and the risk factors of serum bile acid spectrum causing ICP were analyzed by univariate and multivariate logistic regression.
Appetite
March 2025
University of South Alabama, Department of Psychology; Rogers Behavioral Health, Research Center. Electronic address:
In emotional eating (EE), affective states influence desire to eat and/or eating behavior. Most research on EE focuses on over-/under-eating in response to negative emotions, the former of which is related to higher weight and binge-spectrum eating disorder (ED) symptoms while the latter has been implicated in low weight and restrictive-only ED. Individuals endorsing both forms of negative EE are more impaired than those reporting unidirectional negative EE.
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