A 58-year-old woman with chronic renal failure had been undergoing maintenance hemodialysis. Ampulla cardiomyopathy recurred in association with prolonged sympathetic nerve function disorder. Periodical evaluation of the patient's condition using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy was continued since the first attack at age 55 years. The initial washout rate was high at 58.3%, and was still high at 33.0% when she was discharged following improvement in wall motion, and remained high at 45.4% 1 year after discharge. Recurrence occurred at age 58 years, when a high washout rate of 48.6% was observed. High washout rate values of 49.5% and 40.1% were also observed 2 and 9 months after discharge, respectively, following improvement in wall motion abnormalities. 123I-MIBG can be used to assess the course of recurrent ampulla cardiomyopathy, and can objectively evaluate sympathetic nerve function disorders. This interesting case suggests that sympathetic nerve function disorder is closely related to the pathophysiology of this disorder.
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