The submitted review gives an account of therapeutic and prophylactic indications in oncology, in aimed, not aimed (empirical) treatment of febrile neutropenic patients, prophylaxis of infection during neutropenic episodes and selective decontamination before and during transplantation of bone marrow, focused on new antimicrobial and antimycotic agents.
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A sterilization method for human decellularized vaginal matrices.
Sci Rep
December 2024
Department of Medical Microbiology and Infection Prevention, Amsterdam UMC - Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Vaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. Decellularized vaginal matrices (DVMs) from human tissue offer a promising alternative, but require effective sterilization to ensure safety and functionality.
View Article and Find Full Text PDFExploring the probiotic potential of yeast strains isolated from ripe banana and plantain peels: in vitro and in vivo assessment.
Int Microbiol
December 2024
Department of Biological Sciences, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.
Probiotics have been shown to improve host access to vitamins, generate vitamins and improve gastrointestinal tract functions throughout transit yeasts which are indicated to potentially function as probiotics with some health benefits. The aim of this study was to evaluate the probiotic potential of yeast isolates from banana and plantain peels. Yeast strains were isolated from ripe banana and plantain peels, using the standard procedures.
View Article and Find Full Text PDFGenome-based analysis of biosynthetic potential from antimycotic Streptomyces rochei strain A144.
FEMS Microbiol Lett
January 2024
Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences/Xinjiang Key Laboratory of Special Environmental Microbiology, Urumqi 830091, PR China.
Streptomyces rochei is a species of Streptomyces with a diverse range of biological activities. Streptomyces rochei strain A144 was isolated from desert soils and exhibits antagonistic activity against several plant pathogenic fungi. The genome of S.
View Article and Find Full Text PDFSynthesis and antimycotic activity of new derivatives of imidazo[1,2-]pyrimidines.
Beilstein J Org Chem
November 2024
Organic Chemistry Department, RUDN University, 6 Miklukho-Maklaya St., 117198 Moscow, Russian Federation.
The heterocyclic core of imidazo[1,2-]pyrimidine was formed in satisfactory yields as a result of the interaction of the readily available 2-aminoimidazole with -substituted maleimides or -arylitaconimides. The mechanism of the studied processes was postulated basing on experimental data, HPLC-MS analysis of reaction mixtures, and quantum chemical calculations. Molecular docking results of the obtained imidazo[1,2-]pyrimidines, when compared with voriconazole, a drug already in clinical use, suggest that they may possess antifungal activity against .
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