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| http://dx.doi.org/10.3201/eid1303.061059 | DOI Listing |
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Platelet aggregation responses to Typhimurium are determined by host anti- antibody levels.
Platelets
December 2024
Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Invasive non-typhoidal infections are responsible for >75 000 deaths/year and >500 000 cases/year globally. Seventy-five percent of these cases occur in Sub-Saharan Africa, an increasing number of which are from multi-drug resistant strains. Interactions between bacteria and platelets can lead to thrombus formation, which can be beneficial for control of infection (immunothrombosis), or harmful through uncontrolled inflammation and organ damage (thromboinflammation).
View Article and Find Full Text PDFEvaluation of multi-drug resistance, virulence factors, and antimicrobial resistance genes of non-typhoidal Salmonella isolated from ruminants as a potential human health threat in Razavi Khorasan, northeastern Iran.
Microb Pathog
February 2025
Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address:
Non-typhoidal Salmonella (NTS) is a significant foodborne pathogen that poses a threat to human health by causing infections and potentially acquiring antibiotic resistance. We evaluated thirty-five Salmonella serovars previously isolated from cattle, sheep, goats, and their retail meat in Razavi Khorasan Province, Iran. The isolates were confirmed with Salmonella polyvalent antiserum.
View Article and Find Full Text PDFAntimicrobial prescribing practices for enteric bacterial infections in an integrated health care system, Wisconsin, 2004-2017.
J Infect Public Health
January 2025
Marshfield Clinic Research Institute, Marshfield, WI, United States. Electronic address:
Background: Few studies have evaluated antibiotic prescribing practices for bacterial enteric infections. Unnecessary antibiotics can result in adverse events and contribute to the emergence of antimicrobial resistance. We assessed treatment practices among patients with laboratory-confirmed enteric infections in a regional healthcare system in Wisconsin, USA.
View Article and Find Full Text PDFOne Health approach probes zoonotic non-typhoidal Salmonella infections in China: A systematic review and meta-analysis.
J Glob Health
December 2024
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, Hangzhou; University of Chinese Academy of Sciences, China.
Article Synopsis
- Zoonotic infections like non-typhoidal Salmonella (NTS) are serious public health concerns, especially in China, but there is a lack of integrated studies using the One Health approach to investigate their prevalence and resistance patterns.
- This study employed a systematic review and meta-analysis, examining NTS dynamics over decades, focusing on spatiotemporal prevalence, serovar distribution, and antimicrobial resistance (AMR), utilizing data from multiple databases.
- Findings revealed a 7.35% overall prevalence of NTS, higher in northern China, with poultry as the main source of key serovars; AMR rates were notably high at 73.63%, but showed improvement after a ban on excess use of antimicro
Genomic epidemiology and phenotypic characterisation of Salmonella enterica serovar Panama in Victoria, Australia.
PLoS Negl Trop Dis
November 2024
Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Article Synopsis
- Salmonella enterica serovar Panama is a significant cause of invasive non-typhoidal salmonellosis in Australia, despite being understudied, with a high incidence rate linked to international travel.
- A study analyzed genomic epidemiology and antimicrobial resistance in S. Panama isolates in Victoria from 2000 to 2021, finding that over half exhibited multi-drug resistance, and colistin resistance was identified in one isolate.
- The research also explored the growth dynamics of S. Panama in macrophages, revealing its ability to replicate more effectively compared to S. enterica serovar Typhimurium, although no specific genotype was linked to this enhanced replication.
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