Tripivaloylmethane [systematic name: 4-(2,2-dimethylpropanoyl)-2,2,6,6-tetramethylheptane-3,5-dione], C(16)H(28)O(3), is a 1,3,3'-triketone with C(3) molecular symmetry, prepared by alpha-acylation of 2,2,6,6-tetramethylheptane-3,5-dione with 2,2-dimethylpropanoyl anhydride in the presence of barium metal. The molecules are conformationally chiral and pack so that each molecular site is occupied with equal probability by the two enantiomers. The carbonyl groups of the two superimposed enantiomeric molecules are at an angle of 75.4 (16) degrees .
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Article Synopsis
- The origin of homochirality in biological organisms is still a mystery, with some theories suggesting it may have extraterrestrial roots involving chiral molecules in space.
- A new study shows that specific forms of neutral amino acids can exhibit significant asymmetry in how they break down when exposed to circularly polarized light, challenging previous beliefs about the insignificance of this effect.
- The results indicate that this dissociation could lead to a notable enantiomeric excess, potentially playing a major role in the development of homochirality in biological systems.
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