J Cell Sci
Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK.
Published: June 2007
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http://dx.doi.org/10.1242/jcs.03453 | DOI Listing |
Cancers (Basel)
March 2023
Department of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Background And Aim: While many components of the ECM have been isolated and characterized, its modifications in the specific setting of GBMs have only been recently explored in the literature. The aim of this paper is to provide a systematic review on the topic and to assess the ECM's role in shaping tumoral development.
Methods: An online literature search was launched on PubMed/Medline and Scopus using the research string "((Extracellular matrix OR ECM OR matrix receptor OR matrix proteome) AND (glioblastoma OR GBM) AND (tumor invasion OR tumor infiltration))", and a systematic review was conducted in accordance with the PRISMA-P guidelines.
Cardiovasc Diagn Ther
October 2022
Department of Cardiovascular Surgery, University Heart Center, University Hospital Freiburg, Freiburg, Germany.
The constant improvement of operative techniques offers the possibility of treating an increasing number of patients with complex acute and chronic thoracic aortic pathologies involving the aortic arch. Reliable and durable prosthetic material forms the platform for these approaches. Besides the most important properties like impermeability for blood, infection and thrombotic resistance, there are also properties which are not seen at first glance but can nevertheless play a key role in the healing process and long-term results, such as endothelialization and immunostimulation.
View Article and Find Full Text PDFInt J Mol Sci
September 2022
College of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China.
The extracellular matrix (ECM) is a significant factor in cancer progression. Collagens, as the main component of the ECM, are greatly remodeled alongside cancer development. More and more studies have confirmed that collagens changed from a barrier to providing assistance in cancer development.
View Article and Find Full Text PDFExp Eye Res
October 2021
Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country, Sarriena, S/N, 48940, Leioa, Spain; BioCruces Bizkaia Health Research Institute, Begiker, Cruces Plaza S/N, 48903, Barakaldo, Spain. Electronic address:
The transplantation of expansions of limbal epithelial stem cells (LESC) remains one of the most efficient therapies for the treatment of limbal stem cell deficiency (LSCD) to date. However, the available donor corneas are scarce, and the corneas conserved for long time, under hypothermic conditions (after 7 days) or in culture (more than 28 days), are usually discarded due to poor viability of the endothelial cells. To establish an objective criterion for the utilisation or discarding of corneas as a source of LESC, we characterized, by immunohistochemistry analysis, donor corneas conserved in different conditions and for different periods of time.
View Article and Find Full Text PDFJ Cell Sci
February 2019
Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France
Single cells migrate in a myriad of physiological contexts, such as tissue patrolling by immune cells, and during neurogenesis and tissue remodeling, as well as in metastasis, the spread of cancer cells. To understand the basic principles of single-cell migration, a reductionist approach can be taken. This aims to control and deconstruct the complexity of different cellular microenvironments into simpler elementary constrains that can be recombined together.
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