A prospective comparative study of skin grafting of chronic wounds with and without surgical removal of granulation tissue was done on 51 patients with an objective of finding a better method of skin grafting objectively in the chronic burns wounds. Comparative study was done on those patients who had wounds on both the sides of their body. Wounds present on the right side of the body labeled as Group A were skin grafted after removal of granulation tissue and wounds present on left side of the body labeled as Group B were skin grafted without removal of granulation tissue. There was no significant difference in the comparative bacteriology, graft uptake and cosmetic appearance of the grafts. We found no effect of bacteriology and chronicity of the wounds on the uptake of grafts in the two groups. Serum albumin levels <4 g% was found to be associated with statistically significant decreased graft uptake only in Group A wounds. It was further observed that Group A wounds were associated with more blood loss, less secure haemostasis, prolonged surgical duration and thus more cost of surgery as compared to Group B wounds.
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http://dx.doi.org/10.1016/j.burns.2006.11.012 | DOI Listing |
Water Environ Res
March 2025
School of Civil and Environmental Engineering, Cornell University, Ithaca, New York, USA.
This study reported a successful mainstream B-stage nitritation reactor with sludge granulation that incorporated a side-stream anaerobic reactor to treat municipal wastewater A-stage effluent. With influent COD/N and COD/P ratios of 2.60 and 27.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
March 2025
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, 200025, People's Republic of China.
Background: To analyze intraorbital Hydroxyapatite(HA) implant exposure occurring beyond ten years of implantation and suggest potential contributing factors.
Design: A retrospective cohort study based in the Shanghai Ninth People's Hospital.
Methods: One hundred and one Chinese patients with HA implant exposure were identified, from which 38 patients with implants exposure after ten years of insertion were selected and analyzed for demographic and medical records, clinical manifestations, surgery type, implant size, exposure area, follow-up duration, complications, details regarding prosthesis care, and treatment methods.
Trends Cell Biol
March 2025
Center for Global Health, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA; Autophagy, Inflammation, and Metabolism Center of Biochemical Research Excellence, Albuquerque, NM 87106, USA.
Lysosomes are essential membrane-bound organelles that control cellular homeostasis by integrating intracellular functions with external signals. Their critical roles make lysosomal membranes vulnerable to rupture under various stressors, leading to cellular dysfunction. However, the mechanisms by which cells respond to lysosomal damage have only recently begun to be explored.
View Article and Find Full Text PDFPLoS Genet
March 2025
Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Heterochromatin is a key feature of eukaryotic genomes that serves important regulatory and structural roles in regions such as centromeres. In fission yeast, maintenance of existing heterochromatic domains relies on positive feedback loops involving histone methylation and non-coding RNAs. However, requirements for de novo establishment of heterochromatin are less well understood.
View Article and Find Full Text PDFEnviron Res
March 2025
College of Materials Science and Engineering, Wuhan Textile University, Wuhan, 430200, China.
Using granulated blast furnace slag as raw material, chitosan and NaCl as modifier, chitosan modified granulated blast furnace slag based porous geopolymer (PCG) was prepared under the activation conditions of NaOH and sodium silicate. It was used to wrap different types of lightweight aggregates to obtain PCG-lightweight aggregate shell-core structure (PCG-L). PCG-L was used for the adsorption of Pb.
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