AI Article Synopsis
- - The approach to managing febrile neutropenia has shifted to a risk-based strategy that uses established prediction tools to assess potential complications.
- - The selection of initial antibiotic treatment depends on various patient-specific and institutional factors, including the types of infections commonly seen.
- - There are ongoing changes in the types of bacteria causing these infections and their resistance patterns, making it important to consider local data when following treatment guidelines.
Article Abstract
The management of febrile neutropenia has evolved gradually over the years toward a risk-adapted strategy based on validated prediction rules by risk of complications. The drug choice for empiric therapy is influenced by several factors, either related to the patient or to the institution. Microbiological distribution of offending pathogens and their pattern of susceptibility to antibiotics are continuously changing. New mechanisms of resistance in both Gram-negative and -positive bacteria have emerged. Guidelines and general statements should always be considered with the local epidemiology.
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| http://dx.doi.org/10.1586/14787210.5.3.507 | DOI Listing |
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