The patient was a 40-year-old woman who was diagnosed with a malignant melanoma of the left posterior thigh. Follow-up positron emission tomography (PET)/computed tomography (CT) examination revealed an intensely FDG-avid lesion that predominantly contained fat in the right postero-lateral chest wall involving the latissimus dorsi. Ultrasound-guided fine needle aspirate and core biopsy confirmed the diagnosis of hibernoma rather than melanoma metastasis.
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http://dx.doi.org/10.1097/JTO.0b013e31805fe2a5 | DOI Listing |
Front Nucl Med
October 2024
Radiology Department, The Christie, NHS Foundation Trust, Manchester, United Kingdom.
Hibernomas are rare brown fat tumors that garnered attention in the literature with the increasing use of [F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography ([F] FDG PET/CT) for the staging workup and follow-up of solid malignancies. Despite being benign tumors, they exhibit high metabolic activity due to their thermogenic nature, leading to significant radiotracer uptake on functional imaging. This can pose a challenge in differentiating them from the malignant lesions, especially the fat-containing malignancies such as liposarcoma.
View Article and Find Full Text PDFJ Surg Case Rep
February 2023
Department of Pathology, Japanese Red Cross Society Nagano Hospital, Nagano, Nagano, Japan.
Lipomas are common benign tumors, which are usually located in the subcutaneous tissue. It is relatively rare for lipoma to occur in the intrathoracic cavity, and it is clinically difficult to distinguish it from liposarcoma. We present the case of a 72-year-old man with a chest wall tumor preoperatively diagnosed as liposarcoma, with tumor enlargement with radiological image change to heterogenous and 18F-fluorodeoxyglucose positron emission tomography uptake.
View Article and Find Full Text PDFClin Nucl Med
March 2023
From the Department of Radiology and Nuclear Medicine, Cantonal Hospital Lucerne, Lucerne, Switzerland.
Lipomatous hypertrophy of the interatrial septum (LHIS) is a benign anomaly with low prevalence. Lipomatous hypertrophy of the interatrial septum is asymptomatic in most of the cases and rarely leads to atrial arrhythmias, obstructive flow symptoms, or sudden death. It is mostly diagnosed as an incidental finding in cross-sectional imaging and echocardiography, and increased 18F-FDG uptake on LHIS has been described.
View Article and Find Full Text PDFEndocrinol Diabetes Metab Case Rep
March 2020
Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Disease (NIDDK).
Summary: Pheochromocytoma (PHEO) in multiple endocrine neoplasia type 1 (MEN1) is extremely rare. The incidence is reported as less than 2%. We report a case of a 76-year-old male with familial MEN1 who was found to have unilateral PHEO.
View Article and Find Full Text PDFJ Comput Assist Tomogr
October 2019
From the Musculoskeletal Division, Department of Diagnostic Radiology.
We present 5 cases of intraosseous hibernoma, a rare benign tumor of brown fat. Our literature review reveals that the average age at presentation is 58.6 years, and 69.
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