We report two cases of cardiac transplantation of donor hearts with left anterior descending (LAD) myocardial bridging (MB). In the first case, the diagnosis was done only days after transplant. In the second case, a pre-operative angiography showed evidence of LAD myocardial bridging and the organ was used for a marginal recipient. Both patients tolerated the procedure very well and did not have peri-operative cardiac complications. In this study, MB is discussed and its relationship to rejection of donor hearts is evaluated. In light of the growing demand for donated hearts, and in consideration of the relatively high and often undiagnosed occurrence of MB, a liberalized approach to acceptance of this anatomic variant could be adopted in the selection of donor hearts. Identification of MB in the prospective donor heart should not be an absolute contraindication for transplantation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.healun.2007.03.006 | DOI Listing |
Rheumatology (Oxford)
March 2025
Department of Medicine, McMaster University, Hamilton, ON, Canada.
ANCA-associated vasculitis (AAV) is a heterogeneous autoimmune disease marked by varying organ involvement and outcomes. Plasma exchange, a method of removing native plasma and replacing it with crystalloid, albumin or donor plasma, can deplete autoantibodies and may help control autoimmune diseases rapidly. In AAV, several randomized controlled trials have been performed but, individually, had mixed results.
View Article and Find Full Text PDFCatheter Cardiovasc Interv
March 2025
Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.
Background: The effectiveness and safety of traditional versus dual lumen microcatheter (DLMC)-assisted parallel wiring in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
Aims: To compare traditional versus dual lumen microcatheter (DLMC)-assisted parallel wiring.
Methods: We compared the clinical and angiographic characteristics and outcomes of traditional versus DLMC-assisted parallel wiring after failed antegrade wiring (AW) in a large, multicenter CTO PCI registry.
Pediatr Transplant
May 2025
Division of Cardiothoracic Surgery, Children's Healthcare of Atlanta/Emory University School of Medicine, Georgia.
Background: Heart transplantation in teenagers has not been well studied. Teenage recipients have unique considerations that influence outcomes-complexity of cardiac disease, wide range of donor sizing and age, mechanical support options, and medication nonadherence. We sought to analyze the outcomes of heart transplantation in teenagers, focusing on sex-based disparities.
View Article and Find Full Text PDFBackground: Annually, tropical diseases are a major cause of mortality; for instance, in 2019, neglected tropical diseases (NTDs) caused 150,000 deaths and 19 million DALYs, with sub-Saharan Africa bearing over half the burden and the other concentrations in Asia and South America. Their impact, though significant, is lower than ischemic heart disease and respiratory infections. The World Health Organization is critical in combating these tropical diseases through surveillance, information campaigns and health promotion.
View Article and Find Full Text PDFSci Rep
March 2025
Toronto General Hospital Research Institute, University Health Network, Toronto, M5G 2C4, Canada.
Sodium-glucose cotransporter 2 inhibitors (SGLT2i), such as empagliflozin, have shown remarkable benefits in reducing cardiovascular events and mortality in patients with heart failure irrespective of diabetes. Because of the magnitude of the benefits and broad application in both heart failure with reduced and preserved ejection fraction, there have been concerted efforts to identify a mechanism for the observed benefits. One hypothesis is that SGLT2i act directly on the heart.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!