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Objective: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that suggests that hypermobile Ehlers-Danlos syndrome may be overrepresented in TGD populations. The objective of this retrospective chart review was to determine the prevalence of hypermobile Ehlers-Danlos syndrome syndrome at a gender-affirming primary care clinic.

Methods: A retrospective chart review of medical records was conducted with records between May 2021 and June 2024.

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Trans-arterial omental flap protection for infected femoral artery aneurysm in a patient with Parkes-Weber syndrome.

J Vasc Surg Cases Innov Tech

February 2025

Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

We report a case of a 75-year-old man diagnosed with Parkes-Weber syndrome with an infected common femoral artery aneurysm secondary to chronic venous ulcers and groin infection. Given the symptomatic and rapid enlargement of the aneurysm, emergency aneurysmectomy and crossover femoro-femoral bypass were performed with an omental flap routed intraluminally through the aneurysm of the ipsilateral external iliac artery. The transarterial route enabled the short-cutting of the omental flap and the potential prevention of infection in the adjacent external iliac artery.

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Methylation of and Are Risk Factors and Potential Biomarkers for Cervical Lesions.

World J Oncol

February 2025

Department of Pathology, The Seventh Medical Center, Chinese PLA General Hospital, Beijing 100700, China.

Background: The correlation between methylation of paired box gene 1 () and sex determining region Y-box 1 () with human papillomavirus (HPV) infection and the progression of cervical lesions is not well understood. This study aims to explore the potential value of and as diagnostic biomarkers for cervical diseases.

Methods: A total of 139 cervical biopsy tissue samples were obtained from the Department of Pathology, the Seventh Medical Center, Chinese PLA General Hospital from 2021 to 2023.

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Background: The global prevalence of diabetes has been rising rapidly in recent years, leading to an increase in patients experiencing hyperglycemic crises like diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). Patients with impaired renal function experience a delay in insulin clearance, complicating the adjustment of insulin dosing and elevating hypoglycemia risk. Accordingly, this study aims to evaluate the impact of renal function on the safety and efficacy of insulin use in patients with isolated DKA or combined DKA/HHS.

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Current update on the neurological manifestations of long COVID: more questions than answers.

EXCLI J

November 2024

Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.

Since the outbreak of the COVID-19 pandemic, there has been a global surge in patients presenting with prolonged or late-onset debilitating sequelae of SARS-CoV-2 infection, colloquially termed long COVID. This narrative review provides an updated synthesis of the latest evidence on the neurological manifestations of long COVID, discussing its clinical phenotypes, underlying pathophysiology, while also presenting the current state of diagnostic and therapeutic approaches. Approximately one-third of COVID-19 survivors experience prolonged neurological sequelae that persist for at least 12-months post-infection, adversely affecting patients' quality of life.

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