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White matter hyperintensities and TDP-43 pathology in Alzheimer's disease.
Alzheimers Dement
January 2025
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Introduction: Greater white matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) are seen with transactive response DNA-binding protein 43 (TDP-43) pathology in frontotemporal lobar degeneration (FTLD-TDP). WMH associations with TDP-43 pathology in Alzheimer's disease (AD-TDP) remain unclear.
Methods: A total of 157 participants from Mayo Clinic Rochester with autopsy-confirmed AD, known TDP-43 status, and antemortem fluid-attenuated inversion recovery (FLAIR) MRI were included.
Democratization in abdominal ablation therapies: The impact of percutaneous robotic assistance on accuracy-A systematic review.
J Robot Surg
January 2025
IHU-Strasbourg, Institute of Image-Guided Surgery, 1, Place de l'Hôpital, 67000, Strasbourg, France.
Advances in medical technology have revolutionized minimally invasive procedures. This study aims to determine the status of intra-abdominal ablation therapies, focusing on outcomes regarding technique improvement and benefits related to the learning curve. A systematic search in four databases was performed in March 2024 to identify relevant studies.
View Article and Find Full Text PDFCalorie (energy) labelling for changing selection and consumption of food or alcohol.
Cochrane Database Syst Rev
January 2025
Behaviour and Health Research Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Background: Overconsumption of food and consumption of any amount of alcohol increases the risk of non-communicable diseases. Calorie (energy) labelling is advocated as a means to reduce energy intake from food and alcoholic drinks. However, there is continued uncertainty about these potential impacts, with a 2018 Cochrane review identifying only a small body of low-certainty evidence.
View Article and Find Full Text PDFNatural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review.
JMIR Ment Health
January 2025
Biomedical Informatics Center, Medical University of South Carolina, Charleston, SC, United States.
Background: The use of natural language processing (NLP) in mental health research is increasing, with a wide range of applications and datasets being investigated.
Objective: This review aims to summarize the use of NLP in mental health research, with a special focus on the types of text datasets and the use of social determinants of health (SDOH) in NLP projects related to mental health.
Methods: The search was conducted in September 2024 using a broad search strategy in PubMed, Scopus, and CINAHL Complete.
Advances in our understanding of the estrous cycle and applications for improving targeted reproductive management in livestock.
Domest Anim Endocrinol
January 2025
USDA, ARS, U.S. Meat Animal Research Center, Clay Center, NE, USA.
The scientific discipline of endocrinology has been invaluable to our understanding of the estrous cycle. In the second half of the twentieth century the development of immunoassay technologies provided a rapid and sensitive method to quantify circulating concentrations of reproductive hormones and relate them to stage of the estrous cycle and physiological status of the animal. Ovarian ultrasonography provided the ability to track the growth and regression of ovarian structures within the same animal across the estrous cycle in real time and, in combination with hormonal profiling, accurately identify mechanisms regulating the estrous cycle and early pregnancy.
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