[The extract of compound Radix Scutellariae on mRNA replication and IFN expression of influenza virus in mice].

Objective: To study the extract of compound Radix Scutellariae on inhibiting the mRNA replication and inducing the INF expression of influenza virus in mice's vivo.

Methods: Influenza virus infected mice pneumono-adaption stock A/FM/1/47 (H1N1) evoked mice pneumonia taken as animal model. RT-PCR was adopted to measure the content of influenza virus's mRNA and INF in mice to study the effect of the extract on mRNA replication and IFN expression.

Results: The extract of compound Radix Scutellariae could inhibit influenza virus' s mRNA replication (P < 0.01) and induce interferon expression in mice (P > 0.05).

Conclusion: The extract of compound Radix Scutellariae can induce interferon and inhibit influenza virus replication in mice.