Purpose: This preliminary investigation was a longitudinal study of fast mapping skills in normally developing children, 16-18 months of age. The purpose was to examine the effects of practice on the accessibility of words in lexical memory.
Method: Eight children were taught the names of 24 unfamiliar objects over 12 weekly training sessions. The amount of practice children had with individual words varied as a function of session. Data were compared to a control group of children-matched on productive vocabulary-who were exposed to the same experimental words at the first and last sessions only.
Results: The results showed that for children in the experimental group, extended practice with a novel set of high-practice words led to the rapid acquisition of a second set of low-practice words. Children in the control group did not show the same lexical advantage.
Conclusions: The data suggest that learning some words primes the system to learn more words. Vocabulary development can thus be conceptualized as a continual process of fine-tuning the lexical system to enable increased accessibility to information. Implications for the treatment of children with word-finding difficulties are considered.
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http://dx.doi.org/10.1044/1092-4388(2007/048) | DOI Listing |
F1000Res
January 2025
Department of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Introduction: Magnetic resonance imaging (MRI) is essential for brain imaging, but conventional methods rely on qualitative contrast, are time-intensive, and prone to variability. Magnetic resonance finger printing (MRF) addresses these limitations by enabling fast, simultaneous mapping of multiple tissue properties like T1, T2. Using dynamic acquisition parameters and a precomputed signal dictionary, MRF provides robust, qualitative maps, improving diagnostic precision and expanding clinical and research applications in brain imaging.
View Article and Find Full Text PDFISME Commun
January 2025
Department of Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), University Hospital Jena, D-07747 Jena, Germany.
Fecal microbiota filtrate transfer is discussed as a safe alternative to fecal microbiota transfer (FMT) to treat ulcerative colitis. We investigated modulation of viral and bacterial composition during fecal microbiota filtrate transfer followed by FMT in six patients with active ulcerative colitis (where clinical activity improved in three patients after filtrate transfer) and combined 16S ribosomal RNA gene amplicon sequencing with a virome analysis pipeline including fast viral particle enrichment and metagenome mapping to detect frequencies of 45,033 reference bacteriophage genomes. We showed that after antibiotic treatment and during filtrate transfer, the bacterial community typically adopted a stable composition distinct to that before antibiotic treatment, with no change toward a donor community.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Preferred Networks, Inc., Tokyo 100-0004, Japan.
Mapping the chemical reaction pathways and their corresponding activation barriers is a significant challenge in molecular simulation. Given the inherent complexities of 3D atomic geometries, even generating an initial guess of these paths can be difficult for humans. This paper presents an innovative approach that utilizes neural networks to generate initial guesses for reaction pathways based on the initial state and learning from a database of low-energy transition paths.
View Article and Find Full Text PDFMagn Reson Med
January 2025
Department of Radiology, Stanford University, Stanford, California, USA.
Purpose: To provide a fast quantitative imaging approach for a 0.55T scanner, where signal-to-noise ratio is limited by the field strength and k-space sampling speed is limited by a lower specification gradient system.
Methods: We adapted the three-dimensional spiral projection imaging MR fingerprinting approach to 0.
Eur Heart J Imaging Methods Pract
January 2025
A.I. Virtanen Institute, University of Eastern Finland, Neulaniementie 2, 70210 Kuopio, Finland.
Aims: The aim of this study was to develop an ultra-short echo time 3D magnetic resonance imaging (MRI) method for imaging subacute myocardial infarction (MI) quantitatively and in an accelerated way. Here, we present novel 3D T- and T -weighted Multi-Band SWeep Imaging with Fourier Transform and Compressed Sensing (MB-SWIFT-CS) imaging of subacute MI in mice hearts .
Methods And Results: Relaxation time-weighted and under-sampled 3D MB-SWIFT-CS MRI were tested with manganese chloride (MnCl) phantom and mice MI model.
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