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Seasonal Influenza Vaccination Programs in the Americas: A Platform for Sustainable Life-Course Immunization and Its Role for Pandemic Preparedness and Response.
Vaccines (Basel)
December 2024
Country Office for the Dominican Republic, Pan American Health Organization (PAHO)/World Health Organization (WHO), Ensanche La Fé, Santo Domingo 10514, Dominican Republic.
Vaccination is one of the most effective measures to prevent influenza illness and its complications. Since the 1980s, countries and territories in the Americas have progressively implemented influenza vaccination operations in high-risk priority groups-such as older adults, pregnant persons, persons with comorbidities and health workers. In this review, we present the history and progress of the seasonal influenza program in the Americas, how the program contributed to the efficient and timely roll-out of the COVID-19 vaccines during the pandemic, and how the program can be used to promote immunization operations across the life span for existing and future vaccines.
View Article and Find Full Text PDFRespiratory Syncytial Virus: A WAidid Consensus Document on New Preventive Options.
Vaccines (Basel)
November 2024
Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Respiratory syncytial virus (RSV) is a leading cause of respiratory infections, particularly affecting young infants, older adults, and individuals with comorbidities. : This document, developed as a consensus by an international group of experts affiliated with the World Association of Infectious Diseases and Immunological Disorders (WAidid), focuses on recent advancements in RSV prevention, highlighting the introduction of monoclonal antibodies (mAbs) and vaccines. : Historically, RSV treatment options were limited to supportive care and the monoclonal antibody palivizumab, which required multiple doses.
View Article and Find Full Text PDFIntegrated Approaches for the Delivery of Maternal and Child Health Services with Childhood Immunization Programs in Low- and Middle-Income Countries: Systematic Review Update 2011-2020.
Vaccines (Basel)
November 2024
Global Immunization Division, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
: The integration of maternal and child health services (MCH) with routine immunization is an important global health strategy, particularly in low- and middle-income countries (LMICs). However, evidence is lacking regarding the best practices for service integration and the effect of integration on immunization and linked health service outcomes. : We searched publication databases and gray literature for articles published between 2011 and 2020 that include approaches to integrating MCH services with immunizations during the first two years of life in LMICs.
View Article and Find Full Text PDFAwareness and Knowledge of Endocrine-Disrupting Chemicals Among Pregnant Women and New Mothers: A Cross-Sectional Survey Study.
Toxics
December 2024
Department of Social Pediatrics, Institute of Child Health, Hacettepe University, Ankara 06230, Türkiye.
Background/objectives: Endocrine-disrupting chemicals (EDCs) are exogenous substances that interfere with hormone regulation, leading to adverse health outcomes. Despite the wide use of EDCs in daily products like plastics, personal care items, and food packaging, public awareness remains low. Pregnant women and new mothers are particularly vulnerable, as exposure to EDCs during early life stages can have long-term health impacts.
View Article and Find Full Text PDFMaternal Gut Microbiome-Mediated Epigenetic Modifications in Cognitive Development and Impairments: A New Frontier for Therapeutic Innovation.
Nutrients
December 2024
Department of Medicine (Biomedical Genetics), Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02218, USA.
Cognitive impairment in various mental illnesses, particularly neuropsychiatric disorders, has adverse functional and clinical consequences. While genetic mutations and epigenetic dysregulations of several genes during embryonic and adult periods are linked to cognitive impairment in mental disorders, the composition and diversity of resident bacteria in the gastrointestinal tract-shaped by environmental factors-also influence the brain epigenome, affecting behavior and cognitive functions. Accordingly, many recent studies have provided evidence that human gut microbiota may offer a potential avenue for improving cognitive deficits.
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