Unlabelled: Monitoring of hospital performance is increasingly used in the process of improving the quality of health care. Various approaches to quality assessment and publication of the results are discussed. Therefore, a method acceptable for clinicians in the hospitals is urgently needed. As the case mix of the patients differs considerably across hospitals, any assessment based on outcome measures has to be adjusted for the patients' risk profiles. We use a method of calculation and presentation that relates the observed complication rate of one centre to the mean rate that would be expected for similar patients in the other centres. We argue that this procedure might especially meet the demands of clinicians in the centres. Data from 44 hospitals in the German Cypher Stent Registry are used to exemplify the proposed procedure.
Results: A large variation in the cumulative incidence of MACE within 6 months (range 0-12.2%) as well as in the prevalence of selected risk factors was observed across hospitals. Using a logistic prediction model, the differences in risk profiles of the patient populations in the centres resulted in a wide range of expected MACE rates (2.55-5.44%). The outcome of seven centres differed significantly from the expectation.
Conclusion: In comparisons of the outcome quality of hospitals, adjustment for the patients' baseline risk by an appropriate method is indispensable.
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http://dx.doi.org/10.1007/s00392-007-0529-5 | DOI Listing |
Rheumatology (Oxford)
January 2025
Department of Gerontology, CR & WISCO General Hospital, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Objectives: Although patients with arthritis have significantly increased cardiovascular disease (CVD) risk, effective prediction tools remain limited. This study aimed to evaluate the predictive value of the Metabolic Score for Insulin Resistance (METS-IR) for CVD events among Chinese patients with arthritis.
Methods: Using data from the China Health and Retirement Longitudinal Study (CHARLS), we conducted a 7-year prospective cohort study (2011-2018) involving 1,059 patients with arthritis.
Endocrine
January 2025
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Purpose: Adrenocortical carcinoma (ACC) is a rare malignancy known for high rates of recurrence and poor prognosis. Previous studies revealed controversial roles of adjuvant radiation therapy (RT) in patient management. This study aimed to investigate the role of adjuvant RT in postoperative ACC patients.
View Article and Find Full Text PDFJ Pharmacokinet Pharmacodyn
January 2025
Global PK/PD/PMx, Eli Lilly and Company, 8 Arlington Square West, Downshire Way, Bracknell, Berkshire, RG12 1PU, UK.
Brain amyloid beta neuritic plaque accumulation is associated with an increased risk of progression to Alzheimer's disease (AD) [Pfeil, J., et al. in Neurobiol Aging 106: 119-129, 2021].
View Article and Find Full Text PDFArch Orthop Trauma Surg
January 2025
Centre Hospitalier Universitaire de Nîmes, Nîmes, France.
Purpose: The adoption of robotic-assisted total hip arthroplasty (THA) is increasingly widespread, yet its influence on outcomes in outpatient surgery remains uncertain. This study aimed to evaluate whether robotic assistance reduces the rate of 90-day postoperative events in patients undergoing outpatient THA, compared to those in inpatient procedures.
Methods: This historical-prospective cohort study analyzed 706 primary THA cases performed between January 2017 and January 2023 by three senior surgeons.
Eur Stroke J
January 2025
Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: We aimed to assess impairments on health-related quality of life, and mental health resulting from Retinal artery occlusion (RAO) with monocular visual field loss and posterior circulation ischemic stroke (PCIS) with full or partial hemianopia using patient-reported outcome measures (PROMs).
Methods: In a prospective study, consecutive patients with acute RAO on fundoscopy and PCIS on imaging were recruited during their surveillance on a stroke unit over a period of 15 months. Baseline characteristics were determined from medical records and interviews.
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