The aim of the article was determination of diagnostic significance and prognostic evaluation of transvaginal ultra sonography ( TV US) in atypical hyperplasia and early stage of endometrium cancer a complex examination of 58 different age women was carried out. The examination revealed negative prognostic value of endometrial thickness from 12 to 14 mm in reproductive and perimenopausal periods; and endometrial thickness from 9 mm to 12 mm in menopausal period. Endometrial thickness more than 19 mm is pathognomic for early stage of endometrium cancer. The comparative assessment of TV US prognostic evaluation and hysteroscopy showed relatively high frequency of false-negative results obtained by using TV US (14,3% vs. 5,5%).

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