The increase in recreational use of ketamine in France led to the carrying out of a survey aimed at depicting the sociological profiles of French ketamine users, their addictive behaviors, and the characteristics relevant to the use of the substance. This survey is based upon the analysis of 250 questionnaires, 24 semi-directive interviews, and two focus groups. Data was collected between July 2002 and June 2003 among individuals who had used ketamine at least once since January 1, 2001. The respondents were mostly males with a polydrug addiction, aged about 24, with little post-secondary education and no steady job. Ketamine was generally the last substance experimented with throughout their lifetime, as of the age of 22. The article reviews the frequency of ketamine use observed in the population surveyed, as well as the routes of administration, the quantities used, the circumstances of use, the sought-after effects and those experienced, and the risks perceived by the users themselves. The data collected provides working facts to allow for the development and implementation of policies for preventing the use and abuse of ketamine among vulnerable populations.
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http://dx.doi.org/10.1080/02791072.2007.10399859 | DOI Listing |
Prog Neuropsychopharmacol Biol Psychiatry
December 2024
Department of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China. Electronic address:
Background: Craving is a core factor driving drug-seeking and -taking, representing a significant risk factor for relapse. This study aims to identify neuroanatomical biomarkers for quantifying and predicting craving.
Methods: The study enrolled 94 ketamine-dependent users and 103 healthy controls (HC).
World Neurosurg
November 2024
Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Objective: Venous thromboembolism (VTE) is a serious postoperative adverse event after spine surgery. In patients with pain refractory to typical multimodal analgesia regimens after spine surgery, whom are often chronic opioid users, perioperative ketamine is an alternative analgesic that has grown in popularity. The aim of this study is to assess the risk of VTE in chronic opioid users undergoing spine surgery.
View Article and Find Full Text PDFJ Clin Med
October 2024
Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Anesth Analg
November 2024
From the Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Cannabis has been used for recreation and medical purposes for more than a millennium across the world; however, its use's consequences remain poorly understood. Although a growing number of surgical patients are regular cannabis consumers, little is known regarding the pharmacological interactions between cannabis and general anesthetics; consequently, there is not a solid consensus among anesthesiologists on the perioperative management of these patients. The existing evidence about the molecular mechanisms underlying pharmacological interactions between cannabinoids and anesthetic agents, both in animal models and in humans, shows divergent results.
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