A 7-month-old infant was examined for severe right ptosis, strabismus, and noisy breathing. CT revealed a right intranasal mass with areas of calcification, erosion, and extension to the cribriform plate. Surgical resection was performed. Pathologic examination confirmed the diagnosis of nasal chondromesenchymal hamartoma. Ophthalmologists may be among the first medical practitioners to encounter nasal chondromesenchymal hamartoma, a rare, benign neoplasm of the nasal and paranasal sinuses.
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Nasal and paranasal sinus masses can arise from a wide range of conditions, both benign and malignant, as well as congenital or acquired. Diagnosing these masses is often challenging, requiring a combination of nasal endoscopy, imaging studies, and histopathological analysis. Initial imaging frequently involves computed tomography or cone beam computed tomography (CBCT) to evaluate the bony anatomy of the nasal cavity and surrounding sinuses, while magnetic resonance imaging (MRI) is typically used for detailed assessment of soft tissues and to aid in differential diagnosis when the findings are inconclusive.
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Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Laboratory Medicine Program, University Health Network, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada. Electronic address:
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