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Leiomyomas, also known as fibroids, are a group of benign smooth muscle tumors commonly present in premenopausal women. Giant uterine leiomyomas are rare. It is described as giant when it weighs 11.

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This report describes the case of a woman in her late forties with a history of large uterine fibroids who presented to the Emergency Department with colicky suprapubic pain and urinary symptoms. Initial computed tomography (CT) showed uncomplicated acute diverticulitis but despite antibiotic treatment, her condition worsened, and a follow-up CT revealed sigmoid perforation, requiring high anterior resection and subtotal hysterectomy. The case highlights how large fibroids exert external pressure on the colon, impairing motility and increasing the risk of diverticula formation.

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Laparoscopic Management of Giant Hydrosalpinx in a Nulliparous Woman.

J Minim Invasive Gynecol

February 2025

Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China; Zhejiang Provincial Clinical Research Center for Reproductive Health and Disease, Hangzhou, 310016, China; Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility, Hangzhou, 310016, China. Electronic address:

A 26-year-old nulliparous woman with lower abdominal pain, mildly elevated inflammatory markers, normal tumor markers and sonographic findings of an 11.9 × 6.1 cm cystic structure in the right adnexa, was treated with antibiotics for suspected hydrosalpinx.

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Background: Although several risk factors have been suggested for uterine torsion, the pathogenesis is still unclear. Therefore, the current study aims to investigate the pathogenesis of uterine torsion by assessing the histological, histochemical, and immunohistochemical changes that occur in the placenta obtained from uterine torsion cases. Immunohistochemical changes include investigation of the expression of estrogen receptors (ERs), progesterone receptors (PRs), and the vascular endothelial growth factor (VEGF) in the placental tissue.

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Pulmonary trophoblastic deportation in the hystricomorph rodent Lagostomus maximus.

Placenta

February 2025

Laboratorio de Histología y Embriología Descriptiva, Experimental y Comparada, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina; Consejo Nacional de Investigaciones Científicas (CONICET), La Plata, Argentina. Electronic address:

Introduction: Trophoblast has been reported in the lungs of gestating eutherian mammals with hemochorial placenta, including humans, cotton rats, and American hares. This study describes the discovery of trophoblastic-like cells in the lungs of Lagostomus maximus.

Methods: Lung and placenta samples from non-pregnant and pregnant plains viscachas were analyzed using histology and immunohistochemistry.

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