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Sargassum Inundations and the Risk of Hypertension Disorders Among Pregnant Women Living in the French Caribbean Island of Martinique.
Int J Environ Res Public Health
December 2024
Cardiovascular Research Team (UR5_3 PC2E), University of the French West Indies (Université des Antilles), 97200 Fort-de-France, France.
Since 2011, Caribbean territories have experienced massive and repeated sargassum seaweed inundations. Once on shore, sargassum degradation through anaerobic metabolism elicits the release of many noxious molecules, including hydrogen sulfide (HS) and ammonia (NH). HS has been long recognized as a malodorous and highly toxic gas, while chronic exposure has not been extensively explored.
View Article and Find Full Text PDF- and Pathogenic Bacteria-Derived Endotoxins Differently Regulate Human Dendritic Cell Generation and γδ T Lymphocyte Activation.
Biomolecules
December 2024
Center for Gender-Specific Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Lipopolysaccharide (LPS) is a potent endotoxin released at high concentrations in acute infections, causing massive host inflammatory response. Accumulating evidence indicates that dysbiosis-associated chronic low levels of circulating LPS can sustain a prolonged sterile low-grade inflammation that increases the risk of several non-communicable diseases. Interventions aimed at increasing the abundance of beneficial/probiotic bacteria, including , result in reduced inflammation, favoring metabolic and immune health.
View Article and Find Full Text PDF[Uremic Leontiasis Ossea: A Challenge in End-Stage Chronic Kidney Disease. About a Case].
Rev Med Chil
May 2024
Departamento de Nefrología, Clínica Dávila, Santiago, Chile.
Article Synopsis
- Uremic leontiasis ossia (ULO) is a rare condition linked to renal osteodystrophy in patients with end-stage chronic kidney disease (CKD) and secondary hyperparathyroidism (SHPTH), causing bone deformities that can lead to a 'leonine' facial appearance.
- The case study focuses on a 39-year-old female patient undergoing treatment, who exhibited significant symptoms and had elevated parathyroid hormone (PTH) levels, confirmed by CT scans.
- Treatment involves a multidisciplinary approach including surgery and management of SHPTH to correct anatomical issues and prevent further complications.
A Rare Case of Idiopathic Megacolon and Megarectum.
Cureus
December 2024
General Surgery, King's College Hospital London, Dubai Hills, Dubai, ARE.
Idiopathic megacolon and megarectum are rare clinical conditions characterized by irreversible dilation of the colon and rectum without an identifiable organic cause. The underlying pathophysiology remains poorly understood, though hypotheses suggest abnormalities in the enteric nervous system or smooth muscle dysfunction. These conditions present significant diagnostic and therapeutic challenges, especially in cases refractory to conservative treatment.
View Article and Find Full Text PDFA case of massive hemoptysis caused by immunoglobulin G4-related respiratory disease in adults: case report and review of literature.
Front Immunol
January 2025
Department of Respiratory, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated chronic fibro-inflammatory condition, that can involve multiple systems. Immunoglobulin G4-related respiratory disease (IgG4-RRD) is relatively rare, with non-specific clinical symptoms. Hemoptysis is a rare clinical symptom of IgG4-RRD, and cases of massive hemoptysis in adults have not been reported.
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