A computational model of activities performance decrease in Alzheimer's disease.

Int J Med Inform

TIMC-IMAG UMR CNRS 5525 Laboratory, Grenoble, France.

Published: December 2007

This article presents a computational model and a simulation of the decrease of performance in daily living activities due to Alzheimer's disease. The framework offered by the cognitive architecture ACT-R is used to develop the model. Typical errors committed in performing tasks by Alzheimer patients are modelled thanks to different parametrisable memory mechanisms of ACT-R and the disease evolution is represented by the increase of errors in the execution of the task. The model is applied to a cooking activity. Simulation of 100 subjects shows results similar to those realised in a standardized assessment with human subjects. We conclude on the need to introduce executive mechanisms in the modelling of behaviours associated to people with cognitive deficits.

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http://dx.doi.org/10.1016/j.ijmedinf.2007.04.002DOI Listing

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