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Introduction: Both the amniotic membrane biologic dressing and nitrofurazone-impregnated dressing are treatment options for burn wounds.

Objective: To compare the efficacy of these treatments in healing second-degree burns, a randomized clinical trial was conducted among patients with second-degree burns who had no comorbidities or history of addiction and were referred to a burn center in Urmia, Iran, between December 2017 and September 2019.

Materials And Methods: Patients were randomly assigned to one of 2 study groups.

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Amniotic Membrane-Covered Conformer and Fibrin Glue for Toxic Epidermal Necrolysis.

Cornea

April 2021

*Department of Ophthalmology, Queensland Children's Hospital, Brisbane, Australia; †University of Queensland, Herston, Australia; ‡Discipline of Paediatrics and Child Health, University of Queensland, Queensland Children's Hospital, Brisbane, Australia; and §City Eye Centre, Brisbane, Australia.

Purpose: Stevens-Johnson syndrome and its more severe form, toxic epidermal necrolysis, are immunologic disorders that cause widespread blistering of the skin and mucous membranes. Its incidence is higher in children and can lead to long-term disabling ocular surface complications that can be averted with amniotic membrane transplantation early in the disease. To introduce an amniotic membrane treatment technique that is time efficient and minimally invasive but still allows for extensive coverage of the ocular mucosal surfaces to prevent and lessen the severity of the complications from ocular surface sequelae.

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Objective: Utilization of the autologous and allogeneic skin substitutes seems to be a promising treatment option. In this study, the authors used amniotic membrane covered with cultured allogenic fibroblast as a skin substitute in the treatment of acute wounds.

Materials And Methods: Full-thickness wounds were created on rats' dorsum regions and treated with cultured allogenic fibroblast on an acellular amniotic membrane (AAM+F), an acellular amniotic membrane (AAM) alone, an allogenic fibroblast suspension (AFS), or normal saline as a control (C).

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Complex abdominal wall defects: appearances at prenatal imaging.

Radiographics

January 2016

From the Department of Radiology, University of Utah School of Medicine, 30 North 1900 East, Room 1A071, Salt Lake City, UT 84132-2140.

Abdominal wall defects are a complex group of anomalies, and many are incorrectly diagnosed. Evaluation of the defect relative to the umbilical cord insertion site is fundamentally important in differentiating among the various malformations. The two most common abdominal wall defects are gastroschisis, in which the defect is on the right side of the normally inserting cord and free-floating bowel loops are present, and omphalocele, in which the cord inserts on a membrane-covered midline defect.

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Background: Rodent models of abdominal wall defects (AWD) may provide insight into the pathophysiology of these conditions including gut dysfunction in gastroschisis, or pulmonary hypoplasia in exomphalos. Previously, a Scribble mutant mouse model (circletail) was reported to exhibit gastroschisis. We further characterise this AWD in Scribble knockout mice.

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