Congenital epulis of the newborn is a rare soft tissue manifestation that affects infants, involving predominantly the maxillary ridge. When identified, generally at birth, excisional biopsy is recommended to avoid feeding and respiratory disturbances. This article presents a case report of a female infant who was referred to an oral and maxillofacial surgery facility for removal of a fibrotic mass present on the mandibular alveolar ridge. Diagnosis and prompt intervention can prevent expected complications such as failure to thrive or respiratory difficulty. Pediatric and general dentists should be familiar with oral pathologies that may affect the newborn or infants so that early diagnosis and treatment can be accomplished.
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Sinonasal inverted papilloma (SNIP) is less malignant and usually occur in the maxillary sinus. However, cases invading the pterygopalatine fossa are extremely rare. In this article, we describe a rare case of a man in his early 60s who presented with left nasal congestion, headache, epistaxis, and facial numbness.
View Article and Find Full Text PDFPLoS One
December 2024
Faculté de Médecine Dentaire, Groupe de Recherche en Ecologie Buccale, Université Laval, Québec, QC, Canada.
To explore an alternative strategy to chemotherapy to combat oral cancer, natural products and their derivates constitute one promising approach. In the last previous study, we have demonstrated the potential anti-tumor properties of anethole; an aromatic compound abundantly present in nature that serves as a major active ingredient found in plants like anise and fennel. In the current study, we aimed to investigate how this molecule inhibits oral cancer cell proliferation and induces apoptosis.
View Article and Find Full Text PDFAnticancer Res
December 2024
Department of Dental Hygiene, College of Health Science, Eulji University, Seongnam, Republic of Korea
Background/aim: Accumulated evidence indicates that interactions among various stromal cells within the tumor microenvironment (TME) significantly influence cancer progression. Oral cancers not diagnosed at early stages are associated with low five-year survival rates, highlighting the need for substantial improvements in patient outcomes. Understanding the interactions between cancer cells and the tumor microenvironment is crucial for identifying methods and developing treatment strategies that more effectively inhibit tumor progression and metastasis.
View Article and Find Full Text PDFBMC Complement Med Ther
November 2024
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, 20400, Sri Lanka.
Background: Since ancient times many traditional medicine systems around the world have been using different parts of Annona muricata L. (AM), to treat cancer. Indeed, numerous in vitro and in vivo studies also have shown anticancer properties of different solvent extracts of different parts of AM.
View Article and Find Full Text PDFGeorgian Med News
September 2024
Faculty of Clinical and Translational Medicine, Ivane Javakhishvili Tbilisi State University, Georgia.
Unlabelled: Oncology patients frequently face a variety of oral side effects as a result of cancer treatments like chemotherapy, radiation therapy, and targeted therapy. One common issue is periodontitis. Additionally, patients with COVID-19 have reported a range of oral symptoms, including necrotizing periodontal disease.
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