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Drug-induced hyponatremia is an adverse reaction with accelerated electrolyte disturbance. This study reported a rare case of delayed hyponatremia in a 68year-old female with recurrent upper tract urothelial carcinoma after Gemcitabine plus Cisplatin (GC) and Tislelizumab treatment. She had left ureter surgery, recurrence a year later with mildly abnormal kidney function (glomerular filtration rate (GFR) was 54.

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Unlabelled: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of euvolemic hyponatremia, resulting from non-osmotic release of antidiuretic hormone (ADH). SIADH is frequently associated with neurological conditions, including traumatic brain injury (TBI). TBI-associated SIADH usually develops within days to weeks and resolves within a few weeks.

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Article Synopsis
  • - A 13-year-old girl diagnosed with SIADH (Syndrome of Inappropriate Antidiuretic Hormone) after restrictive eating had normal initial brain MRIs, later revealing olfactory neuroblastoma (ONB) 2.5 years post-diagnosis.
  • - Initial treatments for SIADH included fluid restriction, which was somewhat effective, but the condition recurred post-surgery for ONB, indicating persistence of SIADH even after successful tumor removal.
  • - The case emphasizes the need for healthcare providers to consider the possibility of ONB when evaluating children with unexplained SIADH, recommending earlier imaging and endoscopy if no clear cause is found.
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Purpose: We describe a case of bilateral pseudo-uveitis and secondary glaucoma associated with recurrent mantle cell lymphoma (MCL) that was successfully treated with ibrutinib.

Methods: Retrospective case report.

Results: A 75-year-old man presented with uveitis masquerade syndrome while undergoing treatment for MCL with rituximab-bendamustine.

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From Syncope to Pregnancy: A Case Report of Gestational Transient Thyrotoxicosis.

Cureus

September 2024

Department of Endocrinology, Diabetes, and Metabolism, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, PRT.

With a multifactorial etiology, syncope is a fairly common clinical presentation in emergency care. During pregnancy, it can result from hemodynamic and hormonal changes. One such rare cause is hyperthyroidism.

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