AI Article Synopsis
- Research is increasingly focused on how stem cell biology can be applied to medicine, especially regarding tumor development and spread.
- Stem cells might be key players in the transformation of normal cells into cancerous ones, indicating that cancer could stem from issues in stem cell self-renewal.
- Cancer stem cells have been identified in various cancers, and studying them could lead to better predictive tools and targeted treatments for these diseases.
Article Abstract
Research has been increasing in recent years into the application of stem cell biology to clinical medicine, particularly its role in the evolution and metastasis of tumours. Stem cells may be the target cell for malignant transformation, and tumour formation could be considered a disorder of stem cell self-renewal pathways. Cancer stem cells have been identified in acute myeloid leukaemia and in breast and central nervous system tumours. Cancer stem cells may have a specific role in tumour metastasis, and their understanding may provide insights into the development of predictive and prognostic markers and specific therapeutic interventions.
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| http://dx.doi.org/10.1111/j.1445-2197.2007.04096.x | DOI Listing |
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