Osteoporosis in patients with diabetes mellitus.

J Bone Miner Res

Division of Gastroenterology and Endocrinology, Department of Medicine, Philipps-University, Marburg, Germany.

Published: September 2007

AI Article Synopsis

  • Longer life expectancy and low physical activity are linked to rising rates of diabetes and osteoporosis.
  • Diabetes increases the risk of fractures, especially in those with type 1 and type 2 diabetes due to issues with bone health and falls.
  • Strategies to improve bone density and prevent fractures include managing blood sugar levels, preventing vascular issues, and promoting exercise and fall prevention measures.

Article Abstract

Demographic trends with longer life expectancy and a lifestyle characterized by low physical activity and high-energy food intake contribute to an increasing incidence of diabetes mellitus and osteoporosis. Diabetes mellitus is a risk factor for osteoporotic fractures. Patients with recent onset of type 1 diabetes mellitus may have impaired bone formation because of the absence of the anabolic effects of insulin and amylin, whereas in long-standing type 1 diabetes mellitus, vascular complications may account for low bone mass and increased fracture risk. Patients with type 2 diabetes mellitus display an increased fracture risk despite a higher BMD, which is mainly attributable to the increased risk of falling. Strategies to improve BMD and to prevent osteoporotic fractures in patients with type 1 diabetes mellitus may include optimal glycemic control and aggressive prevention and treatment of vascular complications. Patients with type 2 diabetes mellitus may additionally benefit from early visual assessment, regular exercise to improve muscle strength and balance, and specific measures for preventing falls.

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Source
http://dx.doi.org/10.1359/jbmr.070510DOI Listing

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