The volume reflection phenomenon was detected while investigating 400 GeV proton interactions with bent silicon crystals in the external beam H8 of the CERN Super Proton Synchrotron. Such a process was observed for a wide interval of crystal orientations relative to the beam axis, and its efficiency exceeds 95%, thereby surpassing any previously observed value. These observations suggest new perspectives for the manipulation of high-energy beams, e.g., for collimation and extraction in new-generation hadron colliders, such as the CERN Large Hadron Collider.
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http://dx.doi.org/10.1103/PhysRevLett.98.154801 | DOI Listing |
Invest Ophthalmol Vis Sci
December 2024
Department of Ophthalmology, University of Bonn, Bonn, Germany.
Purpose: The relative ellipsoid zone reflectivity (rEZR) is an innovative biomarker for photoreceptor alterations and showed association with disease staging in macular telangiectasia type 2 (MacTel). However, its prognostic relevance for the ellipsoid zone (EZ) loss is unclear.
Methods: Longitudinal spectral-domain optical coherence tomography (SD-OCT) imaging of patients with MacTel from an observational natural history study was used for en face determination of manifest EZ loss.
J Cachexia Sarcopenia Muscle
February 2025
Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK.
J Voice
December 2024
Carl von Ossietzky University Oldenburg, University Clinic for Visceral Surgery, Ammerländer Heerstraße 114-118, 26129 Oldenburg, Germany.
Objective: The care of patients with dysphonia will change due to the growing shortage of specialists, demographic change, and digitalization. To counteract the associated problems in patient care, the LAOLA app demonstrator is to be developed. In the future, patients will receive exercise videos for their training from their treating speech and language pathologist (SLP) via LAOLA.
View Article and Find Full Text PDFFront Pain Res (Lausanne)
December 2024
Anesthesiology, University of California, San Diego, CA, United States.
The neuraxial delivery of drugs for the management of pain and other spinal pathologies is widely employed and is the subject of a large volume of ongoing research with several thousand papers appearing in the past 5 years alone on neuraxial delivery. Several learned texts have been recently published. A number of considerations have contributed to this widespread interest in the development of the use of neuraxial therapeutics to manage pain.
View Article and Find Full Text PDFJ Affect Disord
December 2024
School of Health and Wellbeing, University of Glasgow, Glasgow, UK; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Whether depression and poor sleep interact or have statistically independent associations with brain structure and its change over time is not known. Within a subset of UK Biobank participants with neuroimaging and subjective and/or objective sleep data (n = 28,351), we examined associations between lifetime depression and sleep disruption and their interaction with structural neuroimaging measures, both cross-sectionally and longitudinally. Sleep variables were: self-reported insomnia and difficulty getting up; actigraphy-derived short sleep (<7 h); sustained inactivity bouts during daytime (SIBD); and sleep efficiency.
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