The self-similar Lorentz billiard channel is a spatially extended deterministic dynamical system which consists of an infinite one-dimensional sequence of cells whose sizes increase monotonically according to their indices. This special geometry induces a nonequilibrium stationary state with particles flowing steadily from the small to the large scales. The corresponding invariant measure has fractal properties reflected by the phase-space contraction rate of the dynamics restricted to a single cell with appropriate boundary conditions. In the near-equilibrium limit, we find numerical agreement between this quantity and the entropy production rate as specified by thermodynamics.
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http://dx.doi.org/10.1103/PhysRevLett.98.130601 | DOI Listing |
PLoS One
January 2025
Department of Sport Studies, Faculty of Education Studies, Universiti Putra Malaysia, Selangor, Malaysia.
Introduction: Mental fatigue, a psychobiological state induced by prolonged and sustained cognitive tasks, impairs both cognitive and physical performance. Several studies have investigated strategies to counteract mental fatigue. However, potential health risks and contextual restrictions often limit these strategies, which hinder their practical application.
View Article and Find Full Text PDFBioprocess Biosyst Eng
January 2025
Cell Culture Development, Biogen, 5000 Davis Drive, Research Triangle Park, NC, 27709, USA.
Membrane fouling is a common and complex challenge with cell culture perfusion process in biopharmaceutical manufacturing that can have detrimental effects on the process performance. In this study, we evaluated a method to calculate the hollow fiber membrane resistance at different time points for water and supernatant. In addition, the number of subvisible particles of < 200 nm.
View Article and Find Full Text PDFFront Chem Biol
August 2024
Center for Structure-based Drug Design and Development, Department of Pharmaceutical Sciences, Concordia University Wisconsin, Mequon, WI, United States.
Introduction: Dual specific phosphatases (DUSPs) are mitogen-activated protein kinase (MAPK) regulators, which also serve as drug targets for treating various vascular diseases. Previously, we have presented mechanistic characterizations of DUSP5 and its interaction with pERK, proposing a dual active site.
Methods: Herein, we characterize the interactions between the DUSP5 phosphatase domain and the pT-E-pY activation loop of ERK2, with specific active site assignments.
Mol Imaging Biol
January 2025
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Purpose: Proton exchange rate (K) is a valuable biophysical metric. K MRI may augment conventional structural MRI by revealing brain impairments at the molecular level. This study aimed to investigate the feasibility of K MRI in evaluating brain injuries at multiple epilepsy stages.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Electrical Engineering, College of Engineering, Taif University, Taif, 21944, Saudi Arabia.
This article proposes a novel dual-loop control (DLC) method with a Tilt Integral Derivative (TID) Controller for output voltage regulation and inductor current regulation in a boost converter. The TID controller is designed with the aid of swarm inspired algorithms, particularly Artificial Bee Colony (ABC) and Salp Swarm Optimization (SSO). The TID Controller is a robust, and feedback type of controller and belongs to the family of fractional order controllers.
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