Aim: To describe a situation in which an opioid-dependent patient overcame naltrexone blockade. DESIGN, CASE REPORT, SETTING: Addiction treatment center in St Petersburg, Russia.
Participant: Patient with naltrexone implant.
Intervention: Detoxification.
Measurements: Clinical observations.
Conclusions: It is possible, but very difficult, to overcome naltrexone blockade by using large doses of heroin.
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