In experimental study on 4 mongrel 4-5 year old dogs under intravenous anesthesia (rometar) after turning back of mucous-periosteum flap and forming artificial defects of hard tissues in the upper third of a dental root the defects were filled with glass-ionomer cement (Ketac-molar, 3M-Espe), composite light cured material (Heliomolar flow, Ivoclar-Vivadent), amalgam with high silver content (Amalcap Plus regular non-Gamma-2, Ivoclar-Vivadent) or with material for dental root perforation closure (PRO-Poot mta, Dentsply). It was found that parodontium reacted to these filling materials by inflammation. The glass-ionomer cement and material for dental root perforation closure had lesser effect on parodontium in comparison with composite and amalgam.

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