Context: Involvement of the peripancreatic lymph nodes by tuberculosis is rare and the clinical presentation varies. It can mimic cystic neoplasms of the pancreas.

Case Report: We report the case of a patient having peripancreatic tuberculosis who presented with fever, jaundice, supraclavicular lymphadenopathy and weight loss. Imaging and tumor markers also suggested a pancreatic malignancy. MRI helped to identify the peripancreatic lymph node involvement and biopsy of the supraclavicular lymph node clinched the diagnosis.

Conclusion: Pancreatic and peripancreatic tuberculosis should be considered in the differential diagnosis of cystic lesions of the head of the pancreas.

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