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In vitro Investigation of Antimicrobial and Antioxidant Properties of Green Silver Nanoparticles Synthesized Using Ephedra gerardiana Plant Extract.
Curr Pharm Biotechnol
January 2025
Assistant Professor, Dental Research Center, Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.
Background: The increasing prevalence of antibiotic-resistant bacteria necessitates exploring nanotechnology as a potential solution for microbial elimination.
Objectives: This study aimed to investigate the antimicrobial and antioxidant effects of silver nanoparticles synthesized using aqueous extract from the Ephedra gerardiana (E. gerardiana) plant (EG@AgNPs).
SMALL BUT MIGHTY: CHARACTERIZATION OF VB_SPY_7, A LYTIC PHAGE TARGETING STREPTOCOCCUS PYOGENES.
Georgian Med News
October 2024
1G. Eliava Institute of Bacteriophage, Microbiology and Virology, Tbilisi, Georgia.
The emergence of antibiotic-resistant pathogens necessitates alternative therapies for treating microbial infections, especially in the oral cavity and upper respiratory tract. Our team has developed Phage Pastilles, a controlled-release formulation containing bacteriophages that target common pathogens, including Streptococcus pyogenes, Streptococcus salivarius, Staphylococcus aureus, Enterococcus faecalis, and E. coli.
View Article and Find Full Text PDFAerobic bacteria study, clinical spectrum, and outcome of patients with community-acquired multidrug-resistant pathogens.
J Family Med Prim Care
November 2024
Consultant Clinical Microbiologist, Department of Laboratory Medicine, KIMS SAVEERA Hospital, Anantapur, Andhra Pradesh, India.
Context: Infectious diseases are the leading cause of death in developing countries like India. Hence, even small relative increases in the mortality rate for infections due to multidrug-resistant pathogens would lead to substantial increases in the number of deaths as a result of infections worldwide.
Aims: The aim of the study was to study the microbiological data of community-acquired pathogens and the corresponding outcomes due to antibiotic-resistant versus antibiotic-susceptible bacterial microorganisms.
Antimicrobial activities of seasonally collected bee products: honey, propolis, royal jelly, venom, and mellitin.
Braz J Biol
January 2025
AL-Balqa Applied University, Faculty of Agricultural Technology, Department of Plant Production and Protection, Al-Salt, Jordan.
Ethanolic extracts of seasonally collected natural bee products (honey, propolis, royal jelly (RJ), and bee venom (BV)) were tested for their potential as antimicrobial agents against antibiotic-resistant bacteria and fungi. These extracts exhibited various inhibitory effects on antibiotic-resistant bacteria (Streptococcus pneumoniae, Staphylococcus aureus, MRSA, Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus vulgaris, and Haemophilus influenzae) and fungi (Aspergillus brasiliensis and Candida albicans), with the exception of S. pneumonia, which was not inhibited by honey and RJ extracts, and P.
View Article and Find Full Text PDFPneumococcal disease burden in high-risk older adults: Exploring impact of comorbidities, long-term care facilities, antibiotic resistance, and immunization policies through a narrative literature review.
Hum Vaccin Immunother
December 2024
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, South Korea.
Article Synopsis
- The study reviews the burden of pneumococcal disease in older adults (65+) and highlights how comorbidities and living in long-term care facilities increase risks, especially from antibiotic-resistant strains.
- Research indicates a significant prevalence of antibiotic-resistant serotypes in elderly populations, particularly those with health issues or in LTCFs.
- Vaccination policies differ globally, with some countries using single-dose approaches and others recommending multiple doses; there is a clear need for more targeted vaccination strategies for high-risk elderly individuals.
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