A number of RXR modulators with novel structural features were synthesized and screened in the functional assays. The synthesis and the structure-activity relationship within the series of compounds will be presented. Some in vivo data generated in the models for dyslipidemia and diabetes will also be presented.
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| http://dx.doi.org/10.1016/j.bmcl.2007.01.049 | DOI Listing |
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