Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Objective: Haute Normandie is characterized by the presence of a large number of industries likely to have exposed their employees to a risk of bladder cancer. The objective of the study performed by Assurance Maladie (national health insurance) and Réseau d'Onco-Urologie de Haute Normandie (ROUHN) (Haute Normandie Urological Oncology Network) was to describe the epidemiological characteristics of bladder cancers and to estimate the proportion of potentially work-related cancers.
Material: A questionnaire elaborated for the study and comprising demographic, clinical, environmental and occupational data was completed for all patients in whom exemption of co-payment for bladder cancer was requested in 2003.
Results: The population comprised 258 patients with a mean age of 70.4 years. The sex-ratio was five males for one female. Tumours were diagnosed at an early stage: 73.9% of superficial tumours and 26.1% of invasive lesions. 72.1% of subjects were current smokers or ex-smokers (mean of 32 packet-years). Among the 41% of occupationally exposed subjects, 47.2% were mainly exposed to polycyclic aromatic hydrocarbons, 27.4% to diesel smoke and 17.9% to aromatic amines. Based on a multidisciplinary consultation, 14.7% of patients (n = 38) were considered to be eligible for an occupational disease declaration.
Conclusion: This study demonstrated that the incidence of occupational bladder cancers is underestimated. The urologist plays an essential role in the recognition of all risk factors of bladder cancer, as a history of smoking does not exclude the possibility of an occupational cause.
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http://dx.doi.org/10.1016/s1166-7087(07)92266-6 | DOI Listing |
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