Karyopherins are shuttling transport receptors regulated by the small GTPase Ran, which move cargo between the nucleus and cytoplasm by passing through the nuclear pore complexes. A recent paper in Journal of Cell Biology (Makhnevych et al., 2007) highlights an additional role for karyopherins during mitosis, in regulating the sumoylation status of the septin rings.
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| http://dx.doi.org/10.1016/j.devcel.2007.04.007 | DOI Listing |
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