Heart disease kills as many people as nearly all other causes of death combined. Chronic, progressive, end-stage heart failure results in substantial health care costs and immeasurable suffering for both individuals in particular and society in general. Ventricular assist devices are having an increasing role in supporting patients with severe circulatory compromise. These devices provide support and make it possible for patients to be discharged from the hospital and returned to their communities. System failures and device malfunctions do occur and are the most common cause of death for patients on device support. We present a device malfunction involving a HeartMate XVE Bridge to Transplant that occurred while the patient was at his home, > 100 mi. from our center. The patient was placed on a HeartMate after a re-operative coronary artery bypass surgery. He was discharged to his home on day 43 after device implant. On the 447th post-operative day, two "Red Heart" alarms occurred. After initiating hand pumping of the device, the patient's companion contacted our center, and the local Emergency Medical Service was activated. The patient was transported by helicopter to the Maine Medical Center, where he was placed on a backup pneumatic console and subsequently transferred to a Boston transplant center. The patient subsequently underwent cardiac transplantation. It is imperative to have a definitive strategy and clear support plan to address device malfunctions and system failures. Considering the growing number of ventricular assist device patients discharged home, these occurrences will be more common outside of the hospital setting. Education of clinicians, patients, and their companions, as well as local rescue teams and community hospitals, is essential for successful outcomes and continued quality of life.
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Int J Artif Organs
December 2024
Penn State College of Medicine, Hershey, PA, USA.
Ventricular assist device (VAD) and cardiac transplant patients experience significant strain on their physical and mental wellbeing postoperatively. Mental health and substance use disorders (MHDs and SUDs) have substantial effects on the quality of life and compliance of transplant and VAD patients. In this study, we compare and characterize MHDs and SUDs between VAD and cardiac allograft patients and transplant list patients with and without VADs.
View Article and Find Full Text PDFHeart Fail Rev
December 2024
Division of Cardiology, Tufts Medical Center, Boston, MA, USA.
Left ventricular assist devices (LVAD) have improved mortality and quality of life for patients with end-stage heart failure by providing an alternative to cardiac transplant or as a bridge to transplantation. The improvement in functional capacity however is minimal to modest depending on the right ventricular function, optimal hemodynamics on LVAD therapy, and comorbidities. There is improvement in submaximal exercise capacity but improvement in peak aerobic capacity is limited.
View Article and Find Full Text PDFASAIO J
October 2024
From the Division of Cardiovascular Critical Care, Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts.
Patients with restrictive cardiomyopathy (RCM) and hypertrophic cardiomyopathy (HCM) were previously considered poor candidates for mechanical circulatory support due to technical limitations related to restrictive ventricular physiology and small ventricular size, limiting the ability to provide adequate flows and decompress the heart. Literature examining use of extracorporeal membrane oxygenation (ECMO) in this population consists of a single case series reporting no survivors. We report our experience providing ECMO in children with RCM or HCM at a large pediatric quaternary cardiac center.
View Article and Find Full Text PDFASAIO J
December 2024
Department of Pediatrics, Children's Hospital of Colorado, Aurora, Colorado.
As the Fontan population grows, understanding successful strategies for ventricular assist device (VAD) support of the failing Fontan circulation is needed. We performed a retrospective analysis of patients with Fontan circulation and systemic VAD support in the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry. Competing outcomes and Kaplan-Meier estimated survival methods were used.
View Article and Find Full Text PDFFront Cardiovasc Med
December 2024
Department of Ultrasonography, Shenzhen Children's Hospital, Shenzhen, China.
Background: Percutaneous extracorporeal membrane oxygenation (ECMO) is administered to pediatric patients with cardiogenic shock or cardiac arrest. The traditional method uses focal echocardiography to complete the left ventricular measurement. However, echocardiographic determination of the ejection fraction (EF) by manual tracing of the endocardial borders is time consuming and operator dependent.
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