Aim: To observe the tendency of decreased prevalence of H pylori infection in a 14 year-period and observe the prevalence of intestinal metaplasia and gastric cancer.
Methods: All patients who were diagnosed with dyspepsia and underwent esophagogastroduodenoscopy in Cikini hospital Jakarta from January 1998 until December 2005 were evaluated. We evaluated the histopathologic result of H pylori, the presence of intestinal metaplasia and gastric cancer. Data was grouped for 1 year period of time and was presented descriptively.
Results: Decreased prevalence of H. Pylori infection was found, from 12.8% in 1998, 12.4% in 1999, 14.7% in 2000, 9.6% in 2001, 11.9 % in 2002, 3.8% in 2003, 2.3% in 2004, 2.9% in 2005. Intestinal metaplasia was 4.7% in 1998, 3.2% in 1999, 3.1% in 2000, 2.3 % in 2001, 7.6% in 2002, 8.3% in year 2003, 6.5% in 2004, 7.1% in 2005. Prevalence of gastric cancer was 2.2% in 1998, 0.25% in 1999, 1.1% in 2000, 1.1% in 2001, 1.1% in 2002, 1.8% in 2003, 1.7% in 2004, 3.9% in 2005.
Conclusion: There was decreased prevalence of H pylori infection in 8 year-period but there was no decreased prevalence of intestinal metaplasia and gastric cancer found.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Helicobacter pylori infection is associated with significant elevations to fecal calprotectin, systemic inflammatory markers.
J Pediatr Gastroenterol Nutr
January 2025
Department of Pediatrics, Division of Pediatric Gastroenterology, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Objectives: Fecal calprotectin (FC) is a marker commonly used in the diagnosis and follow-up of inflammatory bowel diseases (IBD). However, other gastrointestinal conditions, like H. pylori (HP) infection, can result in increased neutrophil activity as well.
View Article and Find Full Text PDF() infection can cause a wide range of gastrointestinal disorders, including chronic nonatrophic gastritis, multifocal atrophic gastritis, peptic ulcer disease, gastric adenocarcinoma, and extra-nodal B-cell lymphoma. Although the prevalence of infection has decreased among adults, it is still very common. Approximately 90% of gastric adenocarcinomas are associated with infection.
View Article and Find Full Text PDFCausal Relationship between Helicobacter Pylori Antibodies and Immune Thrombocytopenia: A Mendelian Randomization Study.
Mediterr J Hematol Infect Dis
January 2025
Department of Hematology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Background: Previous observational studies have suggested a potential causal relationship between Helicobacter pylori () infection and immune thrombocytopenia (ITP). However, the evidence for causal inference remains contentious, and the underlying mechanisms require further investigation. To delve deeper into the relationship between and ITP, we conducted a Mendelian randomization (MR) analysis.
View Article and Find Full Text PDFA short communication regarding the trends and prevalence of H. Pylori in unselected gastric mucosal biopsy samples at a tertiary care hospital in Karachi, Pakistan: a five-year retrospective study.
J Pak Med Assoc
January 2025
4th Year MBBS Student, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
A spiral gram-negative bacteria, known as helicobacter pylori, is frequently discovered in the stomach and is linked to a number of clinical disorders. Understanding its prevalence and trends is crucial for both improved clinical outcomes as well as greater epidemiological insight into the region. The current retrospective study was planned to analyse the prevalence and frequency trends of helicobacter pylori in gastric mucosal samples from a Karachi-based tertiary care centre.
View Article and Find Full Text PDFHelicobacter pylori reduces METTL14-mediated VAMP3 mA modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling.
Cell Death Discov
January 2025
Key Laboratory for Experimental Teratology of Chinese Ministry of Education, The Shandong Provincial Key Laboratory of Infection and Immunology, Department of Pathogenic biology, School of basic medical sciences, Cheeloo College of Medicine, Shandong University, Jinan, PR China.
Helicobacter pylori (H. pylori) plays an important role in the malignant transformation of the gastric mucosa from chronic inflammation to cancer. However, the mechanisms underlying the epigenetic regulation of gastric carcinogenesis mediated by H.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!