This is a qualitative study aimed developing an investigative care practice of HIV-positive pregnant woman based on Rosemarie Parse's theory. The study was carried out at a Maternity Ward in Florianópolis, Santa Catarina, Brazil. Its target population included four HIV-positive pregnant women under pre-natal care. The theoretical foundation was applied to the nursing process, taking into account three dimensions: clarifying meaning, synchronizing rhythm, and mobilizing transcendence. Data were collected using interviews and patient observation. The results reveal an innovative method of providing care to HIV-positive pregnant women holistically, thereby, promoting their evolution as human beings.

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