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The assessment of exhaled nitric oxide in patients with obesity and asthma before and after exercise.

J Asthma

January 2025

Division of Pediatric Allergy and Immunology, Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Objective: It is well known that children who suffer from obesity and asthma may also have exercise-induced bronchospasm. Exhaled nitric oxide is an indicator of airway inflammation, and could be affected by exercise. This study looked at how exercise, which is a typical cause of acute airway obstruction, affects the levels of FeNO and in obese and asthmatic children.

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Obesity is a global health concern that promotes chronic low-grade inflammation, leading to insulin resistance, a key factor in many metabolic diseases. Angiotensin 1-7 (Ang 1-7), a component of the renin-angiotensin system (RAS), exhibits anti-inflammatory effects in obesity and related disorders, though its mechanisms remain unclear. In this study, we examined the effect of Ang 1-7 on inflammation of white adipose tissue (WAT) in dietary-induced obese mice.

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The Biorepository and Integrative Genomics (BIG) Initiative in Tennessee has developed a pioneering resource to address gaps in genomic research by linking genomic, phenotypic, and environmental data from a diverse Mid-South population, including underrepresented groups. We analyzed 13,152 genomes from BIG and found significant genetic diversity, with 50% of participants inferred to have non-European or several types of admixed ancestry. Ancestry within the BIG cohort is stratified, with distinct geographic and demographic patterns, as African ancestry is more common in urban areas, while European ancestry is more common in suburban regions.

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Background: Central obesity is a growing public health concern globally, and the recognition of its specific impact on Moroccan demographics remains scarce. This study examined the associations of body mass index (BMI) and central obesity status (WtHR) with sociodemographic characteristics and lifestyle habits in a sample of school-aged children from Marrakech, Morocco.

Methods: The study sample consisted of 1161 children (9.

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What Is Already Known About This Topic?: Childhood overweight and obesity pose significant risks to physical and mental health. The Nutrition Improvement Programme for Rural Compulsory Education Students (NIPRCES) has demonstrated effectiveness in reducing malnutrition.

What Is Added By This Report?: From 2012 to 2023, obesity prevalence increased more rapidly (AAPC=10.

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