Background: Incisional hernias with history of recurrence or infection remain a challenge, with high postoperative morbidity and recurrence rates. The purpose of this study is to evaluate outcomes of patients treated with human cadaveric acellular dermis as an adjunct to abdominal wall reconstruction.
Methods: We retrospectively reviewed 39 abdominal wall reconstructions with human cadaveric acellular dermis performed in 37 patients and compared them with 39 randomly selected cases.
Results: There is a significant decrease in recurrence rates when human cadaveric acellular dermis is added as an overlay to primary closure plus rectus muscle advancement and imbrication in patients with medium-sized hernias. No differences were observed when adding human cadaveric acellular dermis as an overlay to patients with large-size hernias treated with underlay mesh. The use of human cadaveric acellular dermis did not increase postoperative morbidity rates.
Conclusions: Improved results with human cadaveric acellular dermis are obtained by achieving tension-free repairs.
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http://dx.doi.org/10.1097/01.sap.0000254410.91132.a8 | DOI Listing |
Med J Armed Forces India
August 2023
Professor (Anatomy), Christian Medical College, Affiliated to the Tamilnadu Dr. MGR Medical University, Vellore, India.
Background: Fixation preserves the tissues in a close to the life-like state by preventing its autolysis and putrefaction. Formalin has long been considered the close to ideal fixative for histological studies. With the awareness of occupational hazards, a few researchers have tried phenoxetol as a secondary preservative which offered comparable histological results to that of formalin.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Industrial Engineering, Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Background: Transfemoral osseointegrated prostheses, like other uncemented prostheses experience the risk of aseptic loosening and post-operative periprosthetic fractures, with an incidence between 3% and 30%. To date, however, osseointegrated off-the-shelf prostheses are manufactured in a limited number of sizes, and some patients do not meet the strict eligibility criteria of commercial devices. A customized osseointegrated stem was developed and a pre-clinical in vitro investigation of the stem was performed, to evaluate its biomechanical performance.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
January 2025
Cedars-Sinai Medical Centre, Los Angeles, USA.
Objective: Accurate rotational reduction following tibial shaft fracture fixation is absent in up to 36% of cases yet may be critical for lower extremity biomechanics. The objective of this cadaveric study was to compare the results of freehand methods of reduction with software-assisted reduction.
Methods: Four fellowship-trained orthopaedic trauma surgeons attempted rotational correction in a cadaveric model with fluoroscopic assistance (without radiographic visualization of the fracture site) using (1) their method of choice (MoC) and (2) software assistance (SA).
Int J Radiat Oncol Biol Phys
January 2025
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Purpose: This study evaluates the feasibility of utilizing robotic-assisted bronchoscopy with cone beam computed tomography (RB-CBCT) platform to perform low-dose-rate brachytherapy implants (LDR-BT) in a mechanically ventilated human cadaveric model. Post-implant dosimetry was compared to standard stereotactic body radiation therapy plans (SBRT).
Materials And Methods: The RB-CBCT platform was used to place inert LDR-BT seeds into mechanically ventilated human cadavers with percutaneously injected pseudotumors.
J Am Podiatr Med Assoc
January 2025
*Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
Background: Ankle fractures continue to increase in incidence and severity in an older, more challenging geriatric population. Medial malleolus fixation with partially threaded cancellous 4.0-mm screws, a common fixation method, has been shown to fail due to pullout strength.
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