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Cough-Induced Bilateral Internal Carotid Artery Dissection Complicated With Large Vessel Occlusion and Malignant Middle Cerebral Artery Syndrome.
Cureus
September 2024
Department of Stroke Medicine, University Hospitals Dorset NHS Foundation Trust, Bournemouth, GBR.
Article Synopsis
- * A case study of a 55-year-old man highlighted how coughing from a respiratory infection led to severe neurological symptoms and eventual carotid artery dissection.
- * Despite initial treatment with a clot-busting medication called alteplase, the patient faced complications, emphasizing the need for proper diagnosis and management of carotid artery dissection.
Mechanism of electroacupuncture at acupoints of the lung meridian through PKA/PKC regulation of TRPV1 in chronic cough after lung surgery in guinea pigs.
J Thorac Dis
April 2023
Department of Thoracic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Background: Acupuncture has achieved good results in the treatment of cough, asthma, chronic obstructive pulmonary disease (COPD) and other lung diseases, but the mechanism associated with acupuncture in the treatment of chronic cough induced by lung surgery is unknown. We investigated whether acupuncture therapy could improve the symptoms of chronic cough after lung surgery through cyclic-AMp dependent protein kinase A (PKA)/cyclic-AMp dependent protein kinase C (PKC) regulation of the transient receptor potential vanilloid-1 (TRPV1) signaling pathway.
Methods: The guinea pigs were divided into 5 groups: the Sham operation Group (Sham), the Model Group (Model), the Electroacupuncture + Model Group (EA + M), the H89 + Model Group (H89 + M) and the Go6983 + Model Group (Go6983 + M).
Modification of oestrogen signalling pathways influences cough induced by citric acid but not capsaicin in the animal model of both sexes.
Respir Physiol Neurobiol
June 2023
Department of Pathophysiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovakia. Electronic address:
To clarify the role of oestrogen signalling and the role of oestrogen receptor alpha (ERα) in the cough pathways we performed a study in which coughing was observed in both sexes animal models after the treatment by selective ERα degrader fulvestrant (ICI 182-780) and inhibitor of oestrogen synthesis danazol. Degradation of ERα with the normal plasma oestrogen levels induced by fulvestrant, significantly augments the cough response of female but not male guinea pigs. These changes were observed in citric acid-induced cough.
View Article and Find Full Text PDFThe influence of CO on spatiotemporal features of mechanically induced cough in anesthetized cats.
Respir Physiol Neurobiol
January 2023
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, 1333 Center Dr, Gainesville, FL 32603, United States. Electronic address:
Effective cough requires a significant increase in lung volume used to produce the shear forces on the airway to clear aspirated material. This increase in tidal volume during cough, along with an increase in tidal frequency during bouts of paroxysmal cough produces profound hyperventilation and thus reduces arterial CO. While there are several reports in the literature regarding the effects of hypercapnia, hyperoxia, and hypoxia on cough, there is little research quantifying the effects of hypocapnia on the cough reflex.
View Article and Find Full Text PDFPotential high-risk sign of cough-induced transient left bundle branch block in severe aortic valve stenosis.
Eur Heart J Case Rep
May 2022
Division of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
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