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Metabolic alterations in vitamin D deficient systemic lupus erythematosus patients.
Sci Rep
August 2024
Department of Rheumatology and Immunology, The Drum Tower Clinical Medical School of Nanjing Medical University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
Article Synopsis
- - Vitamin D deficiency is common in systemic lupus erythematosus (SLE) patients and correlates with increased disease activity and proteinuria; a study analyzed serum samples to explore metabolic changes related to this deficiency.
- - Using untargeted metabolomics, researchers identified 52 metabolites significantly altered in vitamin D deficient SLE patients, with lipids making up two-thirds of these changes, pointing to disrupted lipid metabolism.
- - Analysis revealed key metabolic pathways impacted, including fat digestion and absorption, and identified potential biomarkers like (S)-Oleuropeic acid and 2-Hydroxylinolenic acid that could aid in diagnosing SLE, demonstrating the connection between vitamin D deficiency and its metabolic effects on the disease.
Simplified equations for object trajectories in rotating space habitats and space juggling.
NPJ Microgravity
October 2023
Department of Physics, North Carolina State University, 2401 Stinson Drive, Box 8202, Raleigh, 27695, NC, USA.
Rotating space habitats provide artificial gravity as a physiological countermeasure for long-term space habitation, though the lived experience of a person in these habitats requires further investigation. Movement planning will require adaptation to the Coriolis and centrifugal forces. The multicultural arts of juggling may offer potential psycho-physiological countermeasures for some individuals and provide interesting insights into movement planning and arts in both microgravity and rotating habitats.
View Article and Find Full Text PDFPropensity of a low-cost adsorbent derived from agricultural wastes to interact with cationic dyes in aqueous solutions.
Environ Monit Assess
August 2023
Environmental Chemistry Laboratory, Resource Management and Environmental Section, Life Science Division, Institute of Advanced Study in Science and Technology, Guwahati, Assam, 781035, India.
Ash collected from thrown-away by-products while preparing a popular traditional food additive, kolakhar of the Assamese community of North East, India, was used as an alternate cost-effective, porous bioadsorbent option from the conventional activated carbon for the purification of carcinogenic dyes laden water. The base material for kolakhar preparation was taken from the discarded banana stem waste to stimulate agricultural waste management. Methylene blue (MB) and basic fuchsin (BF) dyes were used as model cationic dyes.
View Article and Find Full Text PDFDecreased Upward Vertical Movement for Fastballs After Ulnar Collateral Ligament Reconstruction in Major League Baseball Pitchers.
Arthrosc Sports Med Rehabil
October 2022
Missouri Orthopaedic Institute Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri.
Purpose: To analyze the velocity and movement of the 4-seam fastball, curve, and slider thrown before and after ulnar collateral ligament reconstruction (UCLR) in Major League Baseball pitchers using PITCHf/x data.
Methods: Velocity and movement data of the 4-seam fastball, curve, and slider were collected for 3 time frames (12-24 months before the date of UCLR as an uninjured baseline, 12-24 months after the date of UCLR, and 24-36 months after the date of UCLR). Pitchers were separated into 3 age groups (<26, 26 to 31, and >31 years).
Atrial Fibrillation, thromboembolic risk, and the potential role of the natriuretic peptides, a focus on BNP and NT-proBNP - A narrative review.
Int J Cardiol Heart Vasc
December 2022
Department of Cardiology, St James Hospital, James Street, Dublin 8, Ireland.
Atrial fibrillation (AF) is one of the most commonly encountered arrythmia in clinical practice. AF itself can be driven by genetic predisposition, ectopic electrical activity, and abnormal atrial tissue substrates. Often there is no single etiological mechanism, but rather a combination of factors that feed back to remodel and worsen tissue substrate, "AF begets AF".
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