A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Circulating cell-free mRNA in plasma as a tumor marker for patients with primary and recurrent gastric cancer. | LitMetric
Browse Categories

Circulating cell-free mRNA in plasma as a tumor marker for patients with primary and recurrent gastric cancer.

Nobuyuki Tani Daisuke Ichikawa Daito Ikoma Haruhisa Tomita Soujin Sai Hisashi Ikoma Kazuma Okamoto Toshiya Ochiai Yuji Ueda Eigo Otsuji Hisakazu Yamagishi Norimasa Miura Goshi Shiota

Anticancer Res

Department of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.

Published: May 2007

Background: The diagnostic value of circulating mRNA for the early detection of primary and recurrent gastric cancer was evaluated.

Patients And Methods: Circulating hTERT and MUC1 mRNA were amplified in the plasma from 52 gastric cancer patients (40 preoperative and 12 postoperative patients) and 20 healthy controls. The results were compared with those of a circulating cancer cell assay and methylation-specific polymerase chain reaction assay.

Results: Cell-free mRNA of the analyzed genes was detected in 6 (15%) preoperative gastric cancer patients (hTERT: 3 and MUC1: 4 patients) and 2 follow-up patients. These mRNAs were not detected in the plasma from healthy volunteers. There was no correlation between the results of the cell-free mRNA and the other assays.

Conclusion: Detection of circulating cell-free mRNA might serve as a new complementary tumor marker for gastric cancer.

Download full-text PDF

 Source

Publication Analysis

Top Keywords

gastric cancer
20
cell-free mrna
16
circulating cell-free
8
tumor marker
8
primary recurrent
8
recurrent gastric
8
htert muc1
8
cancer patients
8
mrna
6
patients
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

Privacy Policy Site Map

© LitMetric 2025. All rights reserved.