This study assessed the extent of use of the subcutaneous insulin sliding scale (ISS) with hospitalized medical patients and examined the association between ISS use and glucose control. Despite some concerns about efficacy and suitability, the ISS is often used in the hospital studied. Researchers reviewed records of patients with a secondary diagnosis of diabetes who were admitted to the medical teaching unit of a tertiary care hospital. On day 1, 45.2% of patients were on an ISS alone. Patients on an ISS were more likely to experience hyperglycemia compared with patients on scheduled regimens, but they also had fewer hypoglycemic episodes.
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http://dx.doi.org/10.1111/j.1945-1474.2007.tb00181.x | DOI Listing |
J Pathol Inform
January 2025
Department of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, Intelligent Critical Care Center, College of Pharmacy, University of Florida, Orlando, FL, USA.
Human islets display a high degree of heterogeneity in terms of size, number, architecture, and endocrine cell-type compositions. An ever-increasing number of immunohistochemistry-stained whole slide images (WSIs) are available through the online pathology database of the Network for Pancreatic Organ donors with Diabetes (nPOD) program at the University of Florida (UF). We aimed to develop an enhanced machine learning-assisted WSI analysis workflow to utilize the nPOD resource for analysis of endocrine cell heterogeneity in the natural history of type 1 diabetes (T1D) in comparison to donors without diabetes.
View Article and Find Full Text PDFNed Tijdschr Geneeskd
December 2024
Isala, afd. Interne Geneeskunde, Meppel/Zwolle.
PLoS One
November 2024
School of Computer Science, Faculty of Science and Engineering, University of Hull, Hull, United Kingdom.
Type I Diabetes is an endocrine disorder that prevents the pancreas from regulating the blood glucose (BG) levels in a patient's body. The ubiquitous Linear-Quadratic-Integral-Regulator (LQIR) is an optimal glycemic regulation strategy; however, it is not resilient enough to withstand measurement noise and meal disruptions. The Sliding-Mode-Controller (SMC) yields robust BG regulation effort at the expense of a discontinuous insulin infusion rate that perturbs the BG concentrations.
View Article and Find Full Text PDFNutr Clin Pract
November 2024
Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA.
Arch Endocrinol Metab
October 2024
Universidade Católica de Pelotas PelotasRS Brasil Universidade Católica de Pelotas, Pelotas, RS, Brasil.
Objective: To evaluate the effects of medical education on hospital hyperglycemia on physician's technical knowledge and the quality of medical prescriptions, patient care, and clinical outcomes.
Subjects And Methods: The intervention included online classes and practical consultations provided by an endocrinologist to medical preceptors and residents of the Department of Internal Medicine. A pretest and a post-test (0 to 10 points) were applied before and after the intervention and patients medical records were reviewed before and after the intervention.
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